# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA651258 | B | Compound was tested for its inotropic effect by activation of beta-1 adrenergic receptor directly or indirectly; activity values are 70,71 | 1 | ALA1123575 | single protein format | Scientific Literature | ||
2. | ALA667242 | F | 50% increase in myocardial contractility (dP/dt max) in anesthetized dogs on intravenous dose | Canis lupus familiaris | 13 | ALA1123633 | organism-based format | Scientific Literature | |
3. | ALA663755 | F | Hemodynamic activity in anesthetized dog as percent change in left ventricular myocardial activity from baseline (2271 mmHg/s) at 0.01 mg/kg administered intravenously | Canis lupus familiaris | 6 | ALA1124387 | organism-based format | Scientific Literature | |
4. | ALA663756 | F | Hemodynamic activity in anesthetized dog as percent change in left ventricular myocardial activity from baseline (2271 mmHg/s) at 0.03 mg/kg administered intravenously | Canis lupus familiaris | 6 | ALA1124387 | organism-based format | Scientific Literature | |
5. | ALA660682 | F | Hemodynamic activity in anesthetized dog as percent change from baseline (2271 mmHg/s) in left ventricular myocardial activity at 0.1 mg/kg administered intravenously | Canis lupus familiaris | 7 | ALA1124387 | organism-based format | Scientific Literature | |
6. | ALA660683 | F | Hemodynamic activity in anesthetized dog as percent change from baseline (2271 mmHg/s) in left ventricular myocardial activity at 0.3 mg/kg administered intravenously | Canis lupus familiaris | 5 | ALA1124387 | organism-based format | Scientific Literature | |
7. | ALA660684 | F | Hemodynamic activity in anesthetized dog as percent change from baseline (2271 mmHg/s) in left ventricular myocardial activity at 1 mg/kg administered intravenously | Canis lupus familiaris | 5 | ALA1124387 | organism-based format | Scientific Literature | |
8. | ALA672690 | F | Percent maximum increase in cardiac force in anesthetized dogs using isoproterenol as agonist at greater than 4000 nmol/kg | Canis lupus familiaris | 1 | ALA1124004 | organism-based format | Scientific Literature | |
9. | ALA668618 | F | Dose at which 50% maximal effect for cardiac force increase in dogs; Not determined | Canis lupus familiaris | 1 | ALA1124004 | organism-based format | Scientific Literature | |
10. | ALA672688 | F | Compound was tested for inotropic activity by measuring the concentration required to increase cardiac contractile force by 30% in the anesthetized dog after intravenous administration | Canis lupus familiaris | 11 | ALA1123189 | organism-based format | Scientific Literature | |
11. | ALA672071 | F | Compound was tested for inotropic activity by measuring the concentration required to increase heart rate by 15% in the anesthetized dog after intravenous administration | Canis lupus familiaris | 11 | ALA1123189 | organism-based format | Scientific Literature | |
12. | ALA672072 | F | Compound was tested for inotropic activity by measuring the concentration required to mean blood pressure by 20% in the anesthetized dog after intravenous administration | Canis lupus familiaris | 11 | ALA1123189 | organism-based format | Scientific Literature | |
13. | ALA698310 | F | In vitro inhibition of ADP stimulated platelet aggregation in human thrombocyte enriched plasma | Homo sapiens | 13 | ALA1124387 | organism-based format | Scientific Literature | |
14. | ALA698312 | F | In vitro inhibition of collagen stimulated platelet aggregation in human thrombocyte enriched plasma | Homo sapiens | 13 | ALA1124387 | organism-based format | Scientific Literature | |
15. | ALA759160 | B | Inhibition of cAMP PDE III enzyme | Cavia porcellus | 15 | ALA1123633 | protein format | Scientific Literature | |
16. | ALA759853 | B | Inhibition of low Km cyclic AMP phosphodiesterase PDE III of canine ventricle | Canis lupus familiaris | 1 | ALA1123112 | protein format | Scientific Literature | |
17. | ALA821993 | B | Inhibition of platelet cAMP phosphodiesterase | Homo sapiens | 24 | ALA1124004 | assay format | Scientific Literature | |
18. | ALA821994 | B | Inhibition of human platelet cAMP phosphodiesterase at 100 uM | Homo sapiens | 1 | ALA1124004 | assay format | Scientific Literature | |
19. | ALA822704 | B | Inhibition of cAMP Phosphodiesterase enzyme. | 15 | ALA1123575 | protein format | Scientific Literature | ||
20. | ALA1116254 | A | Human intestinal absorption in po dosed human | Homo sapiens | 201 | ALA1157012 | organism-based format | Scientific Literature |