| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA719338 | F | Compound was tested in vivo for exploratory locomotor activity in mice after peroral administration | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA719483 | F | Compound was tested in vivo for exploratory locomotor activity in mice after subcutaneous administration | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 3. | ALA748433 | B | Inhibitory concentration required for in vitro binding affinity to cholinergic central muscarinic receptor on rat brain cortex by using [3H]OXO-M | 8 | assay format | Scientific Literature | |||
| 4. | ALA744135 | B | In vitro displacement of [3H]oxotremorine-M from muscarinic acetylcholine receptor in rat brain cortex | 31 | tissue-based format | Scientific Literature | |||
| 5. | ALA746586 | B | Compound was tested for its binding affinity against M1 human recombinant muscarinic receptor in CHO cells. | 2 | cell-based format | Scientific Literature | |||
| 6. | ALA747856 | B | In vitro displacement of [3H]methylcarbamylcholine from nicotinic acetylcholine receptor in rat brain cortex | 31 | tissue-based format | Scientific Literature | |||
| 7. | ALA747859 | B | Inhibitory concentration required for in vitro binding affinity to cholinergic central Nicotinic acetylcholine receptor on rat brain cortex by using [3H]MCC | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 8. | ALA752535 | B | Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha3-beta2 expressed on cell line sf 9 by using [3H]-MCC | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 9. | ALA857699 | B | Inhibitory concentration required for in vitro binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 expressed on cell line sf 21 by using [3H]-MCC | 6 | assay format | Scientific Literature | |||
| 10. | ALA751849 | B | Compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Rattus norvegicus | 2 | cell membrane format | Scientific Literature | ||
| 11. | ALA777605 | F | The compound was tested for inducing [3H]dopamine release from striatal slices at 10 uM nicotine | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 12. | ALA777606 | F | The compound was tested for inducing [3H]dopamine release from striatal slices at 1 uM nicotine | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA777609 | F | The compound was tested in vivo against effective nicotinic agonistic activity in rat | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA782923 | F | The compound was tested in vivo against effective nicotinic agonistic activity in rat when administered s.c. | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA824188 | F | Compound was tested for inducing stimulation of current response in Xenopus oocytes (alpha3-beta2) at 30 uM | frog | 5 | organism-based format | Scientific Literature | ||
| 16. | ALA824189 | F | Compound was tested for inducing stimulation of current response in Xenopus oocytes (alpha4-beta2) at 1 uM | frog | 4 | organism-based format | Scientific Literature | ||
| 17. | ALA852080 | B | Ratio of IC50 values for displacing [3H]-MCC to [3H]OXO-M | 20 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!