| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1613992 | F | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) | Homo sapiens | 10,316 | ALA1201862 | assay format | PubChem BioAssays | |
| 2. | ALA1614502 | F | PUBCHEM_BIOASSAY: Counterscreen qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. This assay monitors tau fibrillation by fluorescence polarization (FP) of Alexa 594-labeled K18 P301L, which does not fibrillize readily but incorporates into growing filaments of unlabeled tau. (Class of assay: confirmatory) [Related pubchem assays: 596 ] | 23,781 | ALA1201862 | assay format | PubChem BioAssays | ||
| 3. | ALA1777498 | B | Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-dUTP incorporation into DNA strand by rapid plate assay | Vaccinia virus | 28 | ALA1773050 | single protein format | Scientific Literature | |
| 4. | ALA1777499 | A | Cytotoxicity against african green monkey BSC1 cells infected with Vaccinia virus assessed as lactate dehydrogenase release after 20 hrs by microplate reader | Chlorocebus aethiops | 28 | ALA1773050 | cell-based format | Scientific Literature | |
| 5. | ALA1777500 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as change in unfolding transition temperature at 50 uM by thermofluor method | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 6. | ALA1777501 | P | Solubility of the compound in phosphate buffer by chemiluminescence of total nitrogen contents | 5 | ALA1773050 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA1777502 | F | Antiviral activity against Vaccinia virus infected in BSC-1 cells by plaque reduction assay | Vaccinia virus | 28 | ALA1773050 | organism-based format | Scientific Literature | |
| 8. | ALA1777503 | T | Selectivity index, CC50 for African green monkey BSC-1 cells to EC50 for Vaccinia virus | 22 | ALA1773050 | cell-based format | Scientific Literature | ||
| 9. | ALA1777504 | B | Binding affinity at Vaccinia virus WR strain D4 assessed as melting temperature at 50 uM by thermofluor method (Rvb = 38.4 +/- 1.6 degC) | Vaccinia virus WR | 27 | ALA1773050 | single protein format | Scientific Literature | |
| 10. | ALA1794375 | B | PUBCHEM_BIOASSAY: qHTS for inhibitors of binding or entry into cells for Marburg Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249, AID540278] | 83,389 | ALA1201862 | assay format | PubChem BioAssays | ||
| 11. | ALA1794401 | F | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | 91,504 | ALA1201862 | assay format | PubChem BioAssays | ||
| 12. | ALA1794553 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | Homo sapiens | 58,172 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 13. | ALA1794569 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] | 18,965 | ALA1201862 | assay format | PubChem BioAssays | ||
| 14. | ALA1794584 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | ALA1201862 | assay format | PubChem BioAssays | ||
| 15. | ALA2114784 | F | PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) | Homo sapiens | 53,810 | ALA1201862 | assay format | PubChem BioAssays | |
| 16. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | ALA1201862 | assay format | PubChem BioAssays | ||
| 17. | ALA2354254 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) | 153,867 | ALA1201862 | assay format | PubChem BioAssays |
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