# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1116884 | B | Inhibition of PDE9 | 1 | ALA1154916 | assay format | Scientific Literature | ||
2. | ALA1613776 | F | PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) | Homo sapiens | 4,283 | ALA1201862 | assay format | PubChem BioAssays | |
3. | ALA1794311 | F | PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] | 20,122 | ALA1201862 | assay format | PubChem BioAssays | ||
4. | ALA3379674 | B | Inhibition of recombinant PDE9A2 catalytic domain (unknown origin) expressed in Escherichia coli BL21 using [3H]cGMP as substrate after 15 mins by liquid scintillation counting analysis | Homo sapiens | 9 | ALA3351446 | assay format | Scientific Literature | |
5. | ALA3379675 | B | Inhibition of human PDE9A2 using [3H]cGMP as substrate by scintillation proximity assay | Homo sapiens | 1 | ALA3351446 | single protein format | Scientific Literature | |
6. | ALA4385789 | A | Inhibition of PDE1B catalytic domain (10 to 487 residues) (unknown origin) using 3H-cGMP as substrate after 15 mins by liquid scintillation counting method | Homo sapiens | 15 | ALA4385597 | single protein format | Scientific Literature | |
7. | ALA4395172 | B | Inhibition of recombinant N-terminal GST-tagged full length human PDE9A2 expressed in Sf9 cells using F AM-cGMP as substrate at 0.1xIC50 incubated for 60 mins by fluorescence plate reader analysis | Homo sapiens | 1 | ALA4393686 | cell-based format | Scientific Literature | |
8. | ALA4395194 | B | Inhibition of recombinant N-terminal GST-tagged full length human PDE9A2 expressed in Sf9 cells using F AM-cGMP as substrate at 1xIC50 incubated for 60 mins by fluorescence plate reader analysis | Homo sapiens | 1 | ALA4393686 | cell-based format | Scientific Literature | |
9. | ALA4395216 | B | Inhibition of recombinant N-terminal GST-tagged full length human PDE9A2 expressed in Sf9 cells using F AM-cGMP as substrate at 10xIC50 incubated for 60 mins by fluorescence plate reader analysis | Homo sapiens | 1 | ALA4393686 | cell-based format | Scientific Literature | |
10. | ALA4425333 | B | Inhibition of recombinant human PDE9A2 catalytic domain (181 to 506 residues) expressed in Escherichia coli BL21-CodonPlus cells using [3H]cGMP or [3H]cAMP as substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 2 | ALA4425088 | cell-based format | Scientific Literature | |
11. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
12. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |