PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory)
PUBCHEM_BIOASSAY: Late stage results from the probe development efforts to identify inhibitors of Matrix Metalloprotease-13 (MMP-13). (Class of assay: screening) [Related pubchem assays (depositor defined):AID1931, AID570, AID734, AID735, AID769] Panel member name: MMP-8 [IC50 Assay]
PUBCHEM_BIOASSAY: Late stage results from the probe development efforts to identify inhibitors of Matrix Metalloprotease-13 (MMP-13). (Class of assay: screening) [Related pubchem assays (depositor defined):AID1931, AID570, AID734, AID735, AID769] Panel member name: MMP-13 [IC50 Assay]
PUBCHEM_BIOASSAY: Late stage results from the probe development efforts to identify inhibitors of Matrix Metalloprotease-13 (MMP-13). (Class of assay: screening) [Related pubchem assays (depositor defined):AID1931, AID570, AID734, AID735, AID769] Panel member name: MMP-13 [Ki Assay]
Inhibition of MMP1 expressed in Escherichia coli assessed as residual activity using Knight SSP as substrate at 100 uM after 1.5 to 4 hrs by spectrofluorometric analysis relative to control
Inhibition of human MMP2 assessed as residual activity using Knight SSP as substrate at 100 uM after 1.5 to 4 hrs by spectrofluorometric analysis relative to control
Inhibition of MMP3 expressed in Escherichia coli assessed as residual activity using Knight SSP as substrate at 100 uM after 1.5 to 4 hrs by spectrofluorometric analysis relative to control
Inhibition of MMP8 expressed in CHO-K1 cells assessed as residual activity using Knight SSP as substrate at 100 uM after 1.5 to 4 hrs by spectrofluorometric analysis relative to control
Inhibition of MMP12 assessed as residual activity using Knight SSP as substrate at 100 uM after 1.5 to 4 hrs by spectrofluorometric analysis relative to control