| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA652337 | B | Binding affinity towards human Beta-3 adrenergic receptor | 8 | single protein format | Scientific Literature | |||
| 2. | ALA846799 | B | Selectivity towards beta-3 -adrenergic receptor with respect to beta-1-adrenergic receptor | 3 | protein format | Scientific Literature | |||
| 3. | ALA847636 | B | Selectivity towards beta-3 -adrenergic receptor with respect to beta-2-adrenergic receptor | 3 | protein format | Scientific Literature | |||
| 4. | ALA951065 | F | Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 5. | ALA951072 | F | Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 6. | ALA951916 | B | Ratio of EC50 for human beta3 adrenergic receptor over EC50 for human beta-1 adrenergic receptor | Homo sapiens | 43 | assay format | Scientific Literature | ||
| 7. | ALA951917 | B | Intrinsic activity at human beta3 adrenergic receptor expressed in CHO cells assessed as ratio between maximal effect of drug to maximal effect of isoproterenol by EIA | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 8. | ALA951918 | A | Ratio of Cmax for drug to Cmax for [4-(4-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-ethyl}-phenoxy)-phenoxy]-acetic acid in dog at 0.32 or 1.0 mg/kg, po by cassette assay | Canis lupus familiaris | 19 | organism-based format | Scientific Literature | ||
| 9. | ALA951919 | A | Ratio of AUC for drug to AUC for [4-(4-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-ethyl}-phenoxy)-phenoxy]-acetic acid in dog at 0.32 or 1.0 mg/kg, po by cassette assay | Canis lupus familiaris | 19 | organism-based format | Scientific Literature | ||
| 10. | ALA951210 | F | Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by EIA | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 11. | ALA951211 | B | Ratio of EC50 for human beta3 adrenergic receptor over EC50 for human beta2 adrenergic receptor | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 12. | ALA951212 | A | Ratio of Cmax for drug to Cmax for 4'-(2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)-4'-biphenyl-4-carboxylic acid hydrochloride in dog at 0.10 or 0.20 mg/kg, po by cassette assay | Canis lupus familiaris | 17 | organism-based format | Scientific Literature | ||
| 13. | ALA951213 | A | Membrane permeability at pH 6.5 by PAMPA | 17 | assay format | Scientific Literature | |||
| 14. | ALA951220 | A | Cmax in rat at 1.0 mg/kg, po by cassette assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA951221 | A | AUC (0 to 24 hrs) in rat at 1.0 mg/kg, po by cassette assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA951222 | A | Cmax in dog at 3.2 mg/kg, po by cassette assay | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA951223 | A | AUC (0 to 24 hrs) in dog at 3.2 mg/kg, po by cassette assay | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA952033 | A | Cmax in monkey at 1.0 mg/kg, po by cassette assay | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA952034 | A | AUC (0 to 24 hrs) in monkey at 1.0 mg/kg, po by cassette assay | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA952035 | A | Cmax in human at 1.0 mg/kg, po by cassette assay | Homo sapiens | 1 | organism-based format | Scientific Literature |
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