# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA666232 | Binding | Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouse | 70 | ALA1129574 | organism-based format | Scientific Literature | ||
2. | ALA666233 | Binding | Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in rat | 70 | ALA1129574 | assay format | Scientific Literature | ||
3. | ALA665415 | Binding | Inhibition of dihydroorotate dehydrogenase | 1 | ALA1134331 | single protein format | Scientific Literature | ||
4. | ALA1041091 | Functional | Antimalarial activity against Plasmodium falciparum W2mef at 10 uM after 48 hrs by hoechst 33342-thiazole orange stain based flow cytometry assay | Plasmodium falciparum | 27 | ALA1155965 | organism-based format | Scientific Literature | |
5. | ALA759436 | Functional | In vitro inhibition of lymphocyte activated CD2 antigens induced by monoclonal antibody | Homo sapiens | 7 | ALA1130346 | assay format | Scientific Literature | |
6. | ALA759437 | Functional | In vitro inhibition of lymphocyte activated CD25 antigens induced by monoclonal antibody | Homo sapiens | 7 | ALA1130346 | assay format | Scientific Literature | |
7. | ALA857406 | Functional | In vitro inhibition of lymphocyte activated CD71 antigens induced by monoclonal antibody | Homo sapiens | 7 | ALA1130346 | assay format | Scientific Literature | |
8. | ALA812179 | Functional | Inhibition of growth of T-cell lymphoblastoma; range 1-10 uM | 1 | ALA1134331 | assay format | Scientific Literature | ||
9. | ALA984851 | Binding | Inhibition of ubiquinone binding site of Plasmodium falciparum dihydroorotate dehydrogenase | Plasmodium falciparum | 17 | ALA1138463 | single protein format | Scientific Literature | |
10. | ALA984852 | Binding | Inhibition of ubiquinone binding site of human dihydroorotate dehydrogenase | Homo sapiens | 17 | ALA1138463 | single protein format | Scientific Literature | |
11. | ALA967233 | Functional | Inhibition of Concanavalin A-stimulated cell proliferation in mouse splenocytes after 48 hrs by MTT assay | Mus musculus | 6 | ALA1155578 | cell-based format | Scientific Literature | |
12. | ALA967234 | Functional | Inhibition of IL2-dependent mouse CTLL2 cell proliferation after 48 hrs by MTT assay | Mus musculus | 6 | ALA1155578 | cell-based format | Scientific Literature | |
13. | ALA960385 | Binding | Inhibition of Escherichia coli D-alanine-D-alanine ligase B assessed as residual activity at 2 mM preincubated for 30 mins by malachite green assay | Escherichia coli | 16 | ALA1140982 | assay format | Scientific Literature | |
14. | ALA744838 | Functional | The compound was tested for in vitro mixed lymphocyte reaction. | Mus musculus | 8 | ALA1130346 | organism-based format | Scientific Literature | |
15. | ALA882940 | Binding | Inhibitory activity against rat dihydroorotate dehydrogenase | Rattus norvegicus | 4 | ALA1140402 | single protein format | Scientific Literature | |
16. | ALA881227 | Binding | Inhibitory activity against mouse dihydroorotate dehydrogenase | Mus musculus | 5 | ALA1140402 | single protein format | Scientific Literature | |
17. | ALA879486 | Binding | Inhibition of N-terminally truncated recombinant human dihydroorotate dehydrogenase using in vitro enzyme assay | Homo sapiens | 23 | ALA1140402 | single protein format | Scientific Literature | |
18. | ALA880417 | Functional | Inhibitory activity (proliferation) against human peripheral blood mononuclear cells stimulated with Phytohemagglutininin-L | Homo sapiens | 1 | ALA1140402 | assay format | Scientific Literature | |
19. | ALA911102 | Binding | Inhibition of recombinant Plasmodium falciparum DHODH | Plasmodium falciparum | 15 | ALA1139229 | single protein format | Scientific Literature | |
20. | ALA911103 | Binding | Inhibition of human recombinant DHODH | Homo sapiens | 14 | ALA1139229 | single protein format | Scientific Literature |