PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory)
PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709]
Inhibition of recombinant human ALDH2 using propionaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Inhibition of recombinant human ALDH1B1 using propionaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Inhibition of recombinant human ALDH3A1 using benzaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Activation of recombinant human ALDH1A2 using propionaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Activation of recombinant human ALDH1A3 using propionaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Activation of recombinant human ALDH2 using propionaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Activation of recombinant human ALDH1B1 using propionaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Activation of recombinant human ALDH3A1 using benzaldehyde as substrate at 20 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Inhibition of human ALDH1A1 G458N mutant using propionaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis relative to control
Inhibition of recombinant human ALDH1A3 using propionaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Inhibition of recombinant human ALDH1A2 using propionaldehyde as substrate at 100 uM preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis
Inhibition of recombinant human ALDH1A1 using propionaldehyde as substrate preincubated for 2 mins with NAD+ followed by substrate addition by UV-Vis spectrophotometric analysis