| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2114890 | F | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | Homo sapiens | 1,142 | assay format | PubChem BioAssays | ||
| 2. | ALA1816529 | B | Allosteric modulation of gamma-aminobutyric acid receptor A alpha1beta2gamma2S expressed in Xenopus oocytes assessed as potentiation of GABA-mediated chloride current at 1 uM by voltage clamp assay | 4 | cell-based format | Scientific Literature | |||
| 3. | ALA1794456 | F | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | 417 | assay format | PubChem BioAssays | |||
| 4. | ALA1794524 | F | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | 384 | assay format | PubChem BioAssays | |||
| 5. | ALA1794552 | F | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | 320 | assay format | PubChem BioAssays | |||
| 6. | ALA2114782 | F | PubChem BioAssay. qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay. (Class of assay: confirmatory) | 167 | assay format | PubChem BioAssays | |||
| 7. | ALA2114835 | F | PubChem BioAssay. qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion. (Class of assay: confirmatory) | Homo sapiens | 321 | assay format | PubChem BioAssays | ||
| 8. | ALA2114840 | F | PubChem BioAssay. qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay. (Class of assay: confirmatory) | 201 | assay format | PubChem BioAssays | |||
| 9. | ALA2114842 | F | PubChem BioAssay. qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway. (Class of assay: confirmatory) | Homo sapiens | 512 | assay format | PubChem BioAssays | ||
| 10. | ALA1614393 | F | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-012. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | Homo sapiens | 186 | cell-based format | PubChem BioAssays | ||
| 11. | ALA1614458 | F | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] | Homo sapiens | 75,376 | assay format | PubChem BioAssays | ||
| 12. | ALA1614281 | F | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) | Homo sapiens | 12,194 | assay format | PubChem BioAssays | ||
| 13. | ALA1614097 | F | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-024. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | Homo sapiens | 200 | cell-based format | PubChem BioAssays | ||
| 14. | ALA1614215 | F | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-004. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | Homo sapiens | 206 | cell-based format | PubChem BioAssays | ||
| 15. | ALA1614361 | F | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) | Homo sapiens | 16,181 | assay format | PubChem BioAssays | ||
| 16. | ALA1794371 | F | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | 423 | assay format | PubChem BioAssays | |||
| 17. | ALA4022510 | F | Antiinflammatory activity in primary human endothelial keratinocytes assessed as inhibition of IL-17A/TNF-alpha induced IL-8 production preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by HTRF assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 18. | ALA4022511 | F | Antiinflammatory activity in primary human endothelial keratinocytes assessed as inhibition of IL-17A/TNF-alpha induced IL-8 production at 10 uM preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by HTRF assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 19. | ALA4022512 | A | Cytotoxicity against primary human endothelial keratinocytes assessed as inhibition of cell viability preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by PrestoBlue staining based fluorescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 20. | ALA4022513 | A | Cytotoxicity against primary human endothelial keratinocytes assessed as inhibition of cell viability at 10 uM preincubated for 2 hrs followed by cytokine addition measured after 72 hrs by PrestoBlue staining based fluorescence assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature |
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