| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA878916 | F | Tested for its ability to eliminate the infective trypomastigote form of Trypanosoma cruzi, Y strain present in blood of infected mice at the dose of 0.19 mM | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA4021187 | B | Induction of recombinant human NQO-1-mediated superoxide generation assessed as two-electron reduction of compound by measuring SOD-inhibitable reduction of cytochrome c per unit enzyme at 25 umol/ml by spectrophotometric analysis (Rvb = 0.2 +/- 0.1 micromol/L/min) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 3. | ALA4021188 | F | Antihyperproliferative activity against human HaCaT cells after 48 hrs by MTT assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 4. | ALA4021189 | B | Induction of recombinant human CPR-mediated superoxide generation assessed as one-electron reduction of compound by measuring SOD-inhibitable reduction of succinoylated cytochrome c per 2 mU enzyme at 100 umol/ml by spectrophotometric analysis (Rvb = 0.2 +/- 0.1 micromol/L/min) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 5. | ALA4021190 | F | Induction of superoxide generation in human HaCaT cells assessed as 2-OH-E+ oxidized product formation by measuring mean fluorescence intensity at 50 umol/L after 30 mins by flow cytometry (Rvb = 7.1 +/- 5.2 No_unit) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 6. | ALA4021191 | F | Induction of superoxide generation in human HaCaT cells assessed as 2-OH-E+ oxidized product formation by measuring mean fluorescence intensity at 5 umol/L after 18 hrs by flow cytometry (Rvb = 367.5 +/- 80.1 No_unit) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA4021192 | F | Induction of superoxide generation in human HaCaT cells assessed as 2-OH-E+ oxidized product formation by measuring mean fluorescence intensity at 5 umol/L preincubated with 5 umol/L NQO-1 inhibitor dicoumarol for 25 mins followed by compound treatment measured after 18 hrs by flow cytometry (Rvb = 407.59 +/- 68.7 No_unit) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA4021193 | F | Induction of apoptosis in human HaCaT cells at 5 umol/L after 18 hrs by 7-AAD staining based flow cytometry (Rvb = 3 +/- 1%) | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA4021194 | F | Induction of apoptosis in human HaCaT cells at 5 umol/L preincubated with 5 umol/L NQO-1 inhibitor dicoumarol for 25 mins followed by compound treatment measured after 18 hrs by 7-AAD staining based flow cytometry (Rvb = 4.3 +/- 2.6%) | Homo sapiens | 7 | cell-based format | Scientific Literature |
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