# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA720674 | Functional | Tested for its ability to eliminate the infective trypomastigote form of Trypanosoma cruzi, Y strain present in blood of infected mice at the dose of 0.21 mM | Mus musculus | 6 | ALA1130355 | organism-based format | Scientific Literature | |
2. | ALA4390972 | Binding | Inhibition of Schistosoma mansoni DHODH assessed as remaining enzyme activity at 62.5 uM using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay relative to control | Schistosoma mansoni | 1 | ALA4390643 | single protein format | Scientific Literature | |
3. | ALA4390974 | Binding | Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay | Schistosoma mansoni | 28 | ALA4390643 | single protein format | Scientific Literature | |
4. | ALA4390975 | ADME | Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay | Homo sapiens | 28 | ALA4390643 | single protein format | Scientific Literature | |
5. | ALA4390976 | Toxicity | Selectivity Index, ratio of IC50 for human DHODH to IC50 for Schistosoma mansoni DHODH | 12 | ALA4390643 | assay format | Scientific Literature |