# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA700580 | F | Compound was evaluated to potentiate response of AMPA-activated current in Xenopus oocytes expressing Ionotropic glutamate receptor AMPA | 5 | cell-based format | Scientific Literature | |||
2. | ALA700581 | F | Potency on Ionotropic glutamate receptor AMPA in hippocampal neurons | 1 | tissue-based format | Scientific Literature | |||
3. | ALA700582 | F | Compound was evaluated to potentiate response of AMPA-activated current in Xenopus oocytes expressing Ionotropic glutamate receptor AMPA | 3 | cell-based format | Scientific Literature | |||
4. | ALA700583 | F | Compound was evaluated to potentiate response of AMPA-activated current in Xenopus oocytes expressing Ionotropic glutamate receptor AMPA.; NT = Not tested | 1 | cell-based format | Scientific Literature | |||
5. | ALA700584 | F | Compound was evaluated to potentiate response of AMPA-activated current in Xenopus oocytes expressing Ionotropic glutamate receptor AMPA; NT = Not tested | 1 | cell-based format | Scientific Literature | |||
6. | ALA700585 | B | Ability to inhibit [3H]AMPA binding to Ionotropic glutamate receptor AMPA | 4 | single protein format | Scientific Literature | |||
7. | ALA701233 | B | Ability to inhibit [3H]CGS-19,755 binding to Ionotropic glutamate receptor AMPA | 3 | single protein format | Scientific Literature | |||
8. | ALA701234 | B | Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA receptor, using radioligand [3H]- AMPA | 3 | single protein format | Scientific Literature | |||
9. | ALA701235 | B | Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor AMPA, using [3H]TCP as the radioligand. | 1 | single protein format | Scientific Literature | |||
10. | ALA701237 | B | Binding affinity towards AMPA receptor using [3H]AMPA as radioligand; Inactive | 5 | single protein format | Scientific Literature | |||
11. | ALA869260 | F | Antagonist activity against rat GluR1 flop expressed in Xenopus laevis oocyte assessed as inhibition of glutamate-induced current at holding potential -80 mV by two electrode voltage clamp method | Rattus norvegicus | 23 | assay format | Scientific Literature | ||
12. | ALA868050 | F | Antagonist activity against rat GluR1 flop expressed in Xenopus laevis oocyte assessed as inhibition of glutamate-induced current at holding potential -60 mV by two electrode voltage clamp method | Homo sapiens | 10 | assay format | Scientific Literature | ||
13. | ALA868048 | F | Antagonist activity against rat GluR1 flop expressed in Xenopus laevis oocyte assessed as inhibition of glutamate-induced current at holding potential -100 mV by two electrode voltage clamp method | Homo sapiens | 10 | assay format | Scientific Literature | ||
14. | ALA919616 | F | Antagonist activity at rat homomeric recombinant GluR1 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
15. | ALA919623 | F | Antagonist activity at rat homomeric recombinant GluR1 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration at 30 uM by FLIPR assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
16. | ALA920803 | B | Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cells | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
17. | ALA922514 | B | Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
18. | ALA922515 | B | Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assay relative to L-glutamate | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
19. | ALA1838817 | B | Displacement of [3H]AMPA from recombinant rat GluA1 flop isoform receptor expressed in Sf9 insect cell membrane | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
20. | ALA1837938 | B | Displacement of [3H]AMPA from recombinant rat GluA1 receptor flop isoform Y716F mutant expressed in Sf9 insect cell membrane | Rattus norvegicus | 1 | cell-based format | Scientific Literature |