# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3776421 | Binding | Inhibition of rat ROCK2 (2 to 543 residues) at 1 uM by radioactive [33P]-ATP filter binding assay | Rattus norvegicus | 1 | ALA3774338 | single protein format | Scientific Literature | |
2. | ALA3815727 | Binding | Inhibition of rat ROCK2 (2 to 543 residues) assessed as enzyme activity at 1 uM using 33P ATP by radioactive filter binding assay | Rattus norvegicus | 4 | ALA3813616 | single protein format | Scientific Literature | |
3. | ALA3830967 | Binding | Inhibition of rat ROCK2 (2 to 543 residues) assessed as remaining enzyme activity at 50 uM after 30 mins by 33P-ATP filter-binding assay | Rattus norvegicus | 1 | ALA3826966 | single protein format | Scientific Literature | |
4. | ALA829809 | Binding | Inhibition of ROK alpha kinase at 10 uM with 100 uM ATP | Rattus norvegicus | 1 | ALA1137112 | single protein format | Scientific Literature | |
5. | ALA915972 | Functional | Ex vivo inhibition of Rho kinase activity in Sprague-Dawley rat serum at 30 mg/kg, po after 3 hrs | Rattus norvegicus | 10 | ALA1144546 | organism-based format | Scientific Literature | |
6. | ALA915973 | Binding | Ex vivo inhibition of Rho kinase activity in Sprague-Dawley rat serum at 30 mg/kg, po after 1 hrs | Rattus norvegicus | 2 | ALA1144546 | organism-based format | Scientific Literature | |
7. | ALA915974 | Binding | Ex vivo inhibition of Rho kinase activity in Sprague-Dawley rat serum at 30 mg/kg, po after 4 hrs | Rattus norvegicus | 2 | ALA1144546 | organism-based format | Scientific Literature | |
8. | ALA915975 | Binding | Ex vivo inhibition of Rho kinase activity in Sprague-Dawley rat serum at 30 mg/kg, po after 8 hrs | Rattus norvegicus | 2 | ALA1144546 | organism-based format | Scientific Literature | |
9. | ALA887019 | Binding | Inhibition of rat ROCK2 at 1 uM relative to control | Rattus norvegicus | 4 | ALA1139192 | single protein format | Scientific Literature | |
10. | ALA1247624 | Binding | Inhibition of rat ROCK2 expressed in Sf9 cells at 10 uM | Rattus norvegicus | 9 | ALA1240295 | cell-based format | Scientific Literature | |
11. | ALA1249536 | Binding | Inhibition of rat ROCK2 expressed in Sf9 cells at 20 uM | Rattus norvegicus | 3 | ALA1240295 | cell-based format | Scientific Literature | |
12. | ALA1249560 | Binding | Inhibition of rat ROCK2 expressed in Sf9 cells at 50 uM | Rattus norvegicus | 2 | ALA1240295 | cell-based format | Scientific Literature | |
13. | ALA1249584 | Binding | Inhibition of rat ROCK2 expressed in Sf9 cells at 1 uM | Rattus norvegicus | 11 | ALA1240295 | cell-based format | Scientific Literature | |
14. | ALA1249801 | Binding | Inhibition of rat ROCK2 expressed in Sf9 cells | Rattus norvegicus | 3 | ALA1240295 | cell-based format | Scientific Literature | |
15. | ALA1768972 | Binding | Inhibition of rat ROCK2 assessed as residual activity at 10 uM | Rattus norvegicus | 1 | ALA1765070 | single protein format | Scientific Literature | |
16. | ALA4352043 | Binding | Inhibition of rat ROCK2 A9P/S341Q/A342H/S343P mutant (2 to 543 residues) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method | Rattus norvegicus | 1 | ALA4350961 | single protein format | Scientific Literature | |
17. | ALA950832 | Binding | Inhibition of rat ROCK2 at 10 uM | Rattus norvegicus | 1 | ALA1137681 | single protein format | Scientific Literature | |
18. | ALA984699 | Binding | Inhibition of rat ROCK2 expressed in insect Sf9 cells at 10 uM | Rattus norvegicus | 2 | ALA1155855 | cell-based format | Scientific Literature | |
19. | ALA922161 | Binding | Activity of rat ROCK2 kinase at 1 uM | Rattus norvegicus | 1 | ALA1147076 | single protein format | Scientific Literature | |
20. | ALA770788 | Binding | Inhibition of ROCK-II | Rattus norvegicus | 3 | ALA1146654 | single protein format | Scientific Literature |