| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA761210 | F | Inhibition of NGF receptor-induced differentiation of PC12 cells at 100 ug/ml (No effect) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA761211 | F | Induction of NGF receptor-induced differentiation of PC12 cells at 1-100 ug/ml | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA761212 | F | Induction of NGF receptor-induced differentiation of PC12 cells at 100 and 10 ug/ml | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2015243 | B | Inhibition of NGF-induced TrkA receptor phosphorylation in rat PC12 cells at 1 uM after 15 mins by ELISA relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2015244 | B | Inhibition of NGF-induced TrkA receptor phosphorylation in rat PC12 cells at 10 uM after 15 mins by ELISA relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2015245 | B | Inhibition of NGF-induced TrkA receptor phosphorylation in rat PC12 cells at 50 uM after 15 mins by ELISA relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2015246 | B | Inhibition of NGF-induced TrkA receptor phosphorylation in rat PC12 cells after 15 mins by ELISA relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA930423 | B | Induction of TrkA phosphorylation in rat hippocampal neurons at 0.5 uM after 30 mins | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 9. | ALA930424 | B | Induction of TrkA tyrosine phosphorylation in rat hippocampal neurons at 0.5 uM after 30 mins by immunoblotting staining | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 10. | ALA930428 | B | Reversal of TrkA phosphorylation in rat hippocampal neurons at 0.5 uM after 30 mins in presence of K252a | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 11. | ALA926052 | B | Induction of Akt phosphorylation in rat primary hippocampal neurons | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
| 12. | ALA926053 | B | Induction of Akt phosphorylation in rat primary hippocampal neurons at 0.5 uM | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 13. | ALA926054 | B | Induction of Akt phosphorylation in rat primary hippocampal neurons after 30 mins | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
| 14. | ALA3861728 | B | Inhibition of binding of [125I]-NGF to TrkA in rat PC12 cells incubated for 2 hrs by gamma counting method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3861729 | B | Inhibition of NGF-induced TrkA auto-phosphorylation in rat PC12 cells incubated for 15 mins by chemiluminescence based method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4035561 | B | Activation of TrkA in rat PC12 cells assessed as increase in phospho-TrkA levels at 5 to 25 uM after 60 mins by Western blot method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4035562 | B | Potentiation of NGF-induced TrkA phosphorylation in rat PC12 cells at 5 to 25 uM after 60 mins by Western blot method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4308473 | B | Inhibition of TrkA in rat PC12 cells assessed as reduction in beta-NGF-induced neurite outgrowth preincubated for 30 mins followed by beta-NGF stimulation incubated for 7 days by live cell imaging analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4309233 | B | Antagonist activity at TrkA in rat DRG assessed as inhibition of NGF-induced ERK phosphorylation preincubated for 60 mins followed by NGF addition and measured after 30 mins | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 20. | ALA4309234 | B | Antagonist activity at unphosphorylated rat TrkA expressed in baculovirus expression system preincubated for 20 mins followed by TK-substrate-Biotin addition and measured after 35 mins by HTRF assay | Rattus norvegicus | 1 | assay format | Scientific Literature |
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