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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA699595 Binding Binding affinity against Kappa opioid receptor using [3H]U-69593 radioligand in mouse brain homogenates Mus musculus 10 ALA1152046 tissue-based format Scientific Literature 2. ALA700234 Functional Selectivity against kappa receptor in the presence of 0.5 nmol icv SIOM 1 ALA1126784 assay format Scientific Literature 3. ALA716077 Functional Compound was tested for its ability to antagonize the antinociceptive effect of U-69,594 (kappa opioid receptor agonist) in mice Mus musculus 4 ALA1130045 assay format Scientific Literature 4. ALA753138 Binding Binding affinity against opioid receptor kappa using [3H]U-69,593 as a radioligand 9 ALA1125895 single protein format Scientific Literature 5. ALA753139 Binding Binding potency of ethylketocyclazocine to kappa opioid receptor in mouse vas deferens 1 ALA1124394 tissue-based format Scientific Literature 6. ALA753140 Binding Binding affinity for mouse opioid receptor kappa 13 ALA1124598 single protein format Scientific Literature 7. ALA750136 Binding Binding affinities against Opioid receptor kappa 1 of guinea pig brain membrane using [3H]U69,593 as the radioligand using competition binding assays. 9 ALA1124934 assay format Scientific Literature 8. ALA750137 Functional Dose ratio due to Antagonist Effect at a concentration of 100 nM by ethylketazocine, Opioid receptor kappa 1 in mouse vas deferens. 2 ALA1122908 assay format Scientific Literature 9. ALA750138 Functional Antagonism of the antinociceptive effect of Opioid receptor kappa 1 in mice 1 ALA1131607 assay format Scientific Literature 10. ALA750139 Binding Antinociceptive activity evaluated against Opioid receptor kappa 1 in mice by writhing test (administered intravenously) 1 ALA1133681 single protein format Scientific Literature 11. ALA750140 Binding Antinociceptive activity evaluated against Opioid receptor kappa 1 in mice by tail-flick assay (administered intravenously) 1 ALA1133681 tissue-based format Scientific Literature 12. ALA750141 Functional Agonist selectivity for kappa opioid receptor in the naltrindole-treated mice subcutaneous dose of 12.25 umol/kg of norBNI was administered 1 ALA1127305 assay format Scientific Literature 13. ALA750142 Functional Agonist selectivity for kappa opioid receptor in the naltrindole-treated mice. Subcutaneous dose of 12.25 umol/kg of norBNI was administered 2 ALA1127305 assay format Scientific Literature 14. ALA750143 Functional Antagonism of antinociceptive effect of U-50,488 against Opioid receptor kappa 1 in male ICR mice at a sc dose of 16 umol/kg 2 ALA1131147 organism-based format Scientific Literature 15. ALA750144 Functional Antagonism of antinociceptive effect of U-50,488 against Opioid receptor kappa 1 in male ICR mice at a sc dose of 5 umol/kg 1 ALA1131147 organism-based format Scientific Literature 16. ALA750145 Functional Antagonism of antinociceptive effect of U-50,488 against kOpioid receptor kappa 1 in male ICR mice at a sc dose of 1.25 umol/kg 1 ALA1131147 organism-based format Scientific Literature 17. ALA750146 Functional Antagonism of antinociceptive effect of U-50,488 against kOpioid receptor kappa 1 in male ICR mice at a sc dose of 16 umol/kg 1 ALA1131147 organism-based format Scientific Literature 18. ALA882024 Functional Antagonism of antinociceptive effect of U-50,488 against kOpioid receptor kappa 1 in male ICR mice at a sc dose of 5 umol/kg 1 ALA1131147 organism-based format Scientific Literature 19. ALA751010 Functional Antagonist activity against the Opioid receptor kappa 1 using U-50,488H as agonist at 20 pmol/kg (icv) was determined as ratio of ED50 of antagonist to the control (ED50 of control = 27.3 (8.5-52.8) umol/kg) 1 ALA1128224 assay format Scientific Literature 20. ALA751011 Functional Antagonist activity against the kappa opioid receptor using U-50,488H as agonist at 20 pmol/kg (icv) was determined as ratio of ED50 of antagonist to the control (ED50 of control = 27.3 (8.5-52.8) umol/kg) 1 ALA1128224 assay format Scientific Literature