# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA911521 | F | Cytotoxicity against rat astrocytes | Rattus norvegicus | 11 | ALA1149343 | cell-based format | Scientific Literature | |
2. | ALA929304 | F | Increase in P2Y6 receptor protein expression in Wistar rat astrocytes | Rattus norvegicus | 1 | ALA1147977 | cell-based format | Scientific Literature | |
3. | ALA1034272 | F | Astrocyte reversal activity in astrocytes | 5 | ALA1151398 | cell-based format | Scientific Literature | ||
4. | ALA1219302 | F | Neuroprotective activity against glutamate-induced GSH depletion in rat astrocytes assessed as GSH level at 25 uM measured per gram of protein by spectrofluorimetry (RVb = 9.08 +/- 0.9 nmol/kg) | Rattus norvegicus | 5 | ALA1212928 | cell-based format | Scientific Literature | |
5. | ALA1219303 | F | Neuroprotective activity against glutamate-induced ROS production in albino rat astrocytes assessed as dichlorofluresceine produced per gram of protein per 30 mins at 25 uM by spectrofluorimetry (RVb = 4.45 +/- 0.51 nmol) | Rattus norvegicus | 5 | ALA1212928 | cell-based format | Scientific Literature | |
6. | ALA1838752 | F | Increase of EAAT2 expression in mouse primary astrocytes after 24 hrs by Western blot analysis relative to beta-actin protein expression | Mus musculus | 12 | ALA1833913 | cell-based format | Scientific Literature | |
7. | ALA1838753 | F | Increase of EAAT2 expression in mouse primary astrocytes at 10 uM after 24 hrs by Western blot analysis relative to control | Mus musculus | 54 | ALA1833913 | cell-based format | Scientific Literature | |
8. | ALA1838754 | F | Increase of EAAT2 expression in mouse primary astrocytes at 1 uM after 24 hrs by Western blot analysis relative to beta-actin protein expression | Mus musculus | 12 | ALA1833913 | cell-based format | Scientific Literature | |
9. | ALA1838755 | F | Increase of EAAT2 expression in mouse primary astrocytes at 1 uM after 24 hrs by Western blot analysis relative to GAPDH protein expression | Mus musculus | 12 | ALA1833913 | cell-based format | Scientific Literature | |
10. | ALA1838940 | F | Increase of EAAT2 expression in mouse primary astrocytes at 10 uM after 24 hrs by Western blot analysis relative to beta-actin protein expression | Mus musculus | 12 | ALA1833913 | cell-based format | Scientific Literature | |
11. | ALA1838941 | F | Increase of EAAT2 expression in mouse primary astrocytes at 10 uM after 24 hrs by Western blot analysis relative to GAPDH protein expression | Mus musculus | 12 | ALA1833913 | cell-based format | Scientific Literature | |
12. | ALA1838942 | F | Increase of EAAT2 expression in mouse primary astrocytes after 24 hrs by Western blot analysis relative to GAPDH protein expression | Mus musculus | 12 | ALA1833913 | cell-based format | Scientific Literature | |
13. | ALA1838943 | F | Increase of EAAT2 expression in mouse primary astrocytes at <5 uM after 24 hrs by Western blot analysis relative to control | Mus musculus | 3 | ALA1833913 | cell-based format | Scientific Literature | |
14. | ALA1838944 | F | Increase of EAAT2 expression in mouse primary astrocytes at 10 uM after 4 hrs by Western blot analysis relative to control | Mus musculus | 54 | ALA1833913 | cell-based format | Scientific Literature | |
15. | ALA2025120 | F | Neuroprotective activity in rat astrocytes assessed as decrease in LPS-induced nitrite production at 28 to 52 ug/ml after 24 hrs administered 1 hr before LPS challenge by Griess method | Rattus norvegicus | 5 | ALA2021862 | cell-based format | Scientific Literature | |
16. | ALA3383880 | F | Inhibition of LPS-induced NO production in rat astrocytes | Rattus norvegicus | 1 | ALA3352280 | cell-based format | Scientific Literature | |
17. | ALA3383881 | F | Inhibition of LPS-induced NO production in rat astrocytes treated for 1 hr at 10 uM before LPS challenge measured after 24 hrs by Griess assay | Rattus norvegicus | 8 | ALA3352280 | cell-based format | Scientific Literature | |
18. | ALA3372665 | F | Reduction in migration of C57BL/6J mouse brain astrocytes assessed as distance of migration at 100 nM after 8 to 48 hrs by scratch injury assay (Rvb = 700 um) | Mus musculus | 3 | ALA3352556 | cell-based format | Scientific Literature | |
19. | ALA3802383 | F | Neuroprotective activity in H2O2 treated rat astrocytes assessed as induction of NGF release at 10 uM preincubated for 1 hr followed by H2O2 treatment for 24 hrs | Rattus norvegicus | 1 | ALA3797062 | cell-based format | Scientific Literature | |
20. | ALA3879318 | F | Inhibition of H2O2-induced mitochondrial metabolic dysfunction in Sprague-Dawley rat primary astrocytes by resazurin-dye based presto blue assay | Rattus norvegicus | 13 | ALA3877311 | cell-based format | Scientific Literature |