| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA771809 | B | Binding affinity for RasGPR3, guanine nucleotide exchange factor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA771810 | B | Binding affinity for RasGRP, guanine nucleotide exchange factor | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2034158 | B | Modulation of RASGRP3 in human K562 cells assessed as induction of protein activity after 24 hrs by Western blotting analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA979907 | B | Binding affinity to RasGRP3 | 11 | single protein format | Scientific Literature | |||
| 5. | ALA977319 | B | Displacement of [3H]PDBu from RasGRP3 expressed in cells | 36 | cell-based format | Scientific Literature | |||
| 6. | ALA3294519 | B | Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis in presence of phosphatidylserine | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 7. | ALA3294525 | B | Activation of RasGRP3 (unknown origin) overexpressed in HEK293 cells assessed as ERK1/2 phosphorylation at 1 to 10 uM after 30 mins by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3294526 | B | Activation of RasGRP3 (unknown origin) overexpressed in HEK293 cells assessed as protein phosphorylation at T133 at 0.1 to 30 uM after 30 mins by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA3294529 | B | Activation of RasGRP3 (unknown origin) overexpressed in HEK293 cells assessed as ERK1/2 phosphorylation at 0.1 to 30 uM after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA3294530 | B | Activation of RasGRP3 in human Ramos cells assessed as ERK1/2 phosphorylation at 10000 nM after 30 mins by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA3294540 | B | Binding affinity to recombinant human GFP-tagged RasGRP3 expressed in human LNCAP cells assessed as induction of protein translocation from plasma membrane to internal membrane at 10000 nM after 2 to 10 mins by confocal microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA3294541 | B | Binding affinity to recombinant human GFP-tagged RasGRP3 expressed in human LNCAP cells assessed as induction of protein translocation from plasma membrane to internal membrane at 1000 nM after 2 to 10 mins by confocal microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4137136 | B | Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation counting | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 14. | ALA4137141 | B | Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4137143 | B | Activation of GFP-tagged RasGRP3 (unknown origin) expressed in human LNCAP cells after 30 mins by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4137144 | B | Activation of RasGRP3 in human Ramos cells after 30 mins by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4137151 | B | Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4137153 | B | Activation of GFP-tagged RasGRP3 (unknown origin) expressed in human LNCAP cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4137154 | B | Activation of RasGRP3 in human Ramos cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4137165 | B | Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins in presence of phosphatidylserine by scintillation counting | Homo sapiens | 1 | assay format | Scientific Literature |
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