| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1003797 | B | Displacement of [125I]fractalkine from human CX2CR1 expressed in CHO cells at 10 uM | Homo sapiens | 1 | ALA1139391 | cell-based format | Scientific Literature | |
| 2. | ALA951776 | B | Inhibition of CX3CR1 | 1 | ALA1140942 | single protein format | Scientific Literature | ||
| 3. | ALA1291106 | B | Displacement of [125I]-Fractalkine from chemokine CX3CR1 receptor at 1 to 3 uM | 1 | ALA1287688 | single protein format | Scientific Literature | ||
| 4. | ALA1952671 | B | Activity at human CX3CR1 receptor at 10 uM | Homo sapiens | 1 | ALA1949601 | single protein format | Scientific Literature | |
| 5. | ALA2216308 | B | Binding affinity against CX3CR1 at 25 uM | 1 | ALA2203263 | single protein format | Scientific Literature | ||
| 6. | ALA2328018 | B | Antagonist activity at CX3CR1 (unknown origin) assessed as inhibition of chemotaxis at 10 uM | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
| 7. | ALA2328507 | F | Antagonist activity at CX3CR1 (unknown origin) assessed as inhibition of calcium flux at 10 uM | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
| 8. | ALA2328631 | B | Binding affinity to CX3CR1 (unknown origin) at 10 uM by radioligand displacement assay | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
| 9. | ALA2351055 | B | Inhibition of CX3CR1 in human blood monocytes assessed as inhibition of FKN-induced actin polymerization | Homo sapiens | 1 | ALA2346562 | cell-based format | Scientific Literature | |
| 10. | ALA2351085 | B | Displacement of [125I]-CX3CL1 from human CX3CR1 transfected in HEK293 cells after 24 hrs by scintillation counting analysis | Homo sapiens | 51 | ALA2346562 | cell-based format | Scientific Literature | |
| 11. | ALA4037569 | B | Agonist activity at CX3CR1 (unknown origin) | Homo sapiens | 1 | ALA4033786 | single protein format | Scientific Literature | |
| 12. | ALA4037587 | B | Antagonist activity at CX3CR1 (unknown origin) | Homo sapiens | 1 | ALA4033786 | single protein format | Scientific Literature | |
| 13. | ALA4312724 | B | Activity at human CX3CR1 receptor at 10 uM | Homo sapiens | 1 | ALA4311943 | single protein format | Scientific Literature | |
| 14. | ALA4418337 | B | Antagonist activity at CX3CR1 (unknown origin) expressed in mouse B300 cells assessed as inhibition of fractalkine-induced chemotaxis incubated for 30 mins and measured after 3.5 hrs by Cell Titer assay | Homo sapiens | 12 | ALA4418263 | cell-based format | Patent Bioactivity Data | |
| 15. | ALA4630478 | B | Antagonist activity at human Gi/G0-coupled CX3CR1 expressed in CHOK1 cells assessed as inhibition of CX3CL1-induced beta arrestin2 recruitment at 500 nM preincubated for 30 mins followed by CX3CL1 stimulation and measured after 90 to 180 mins by pathhunter assay | Homo sapiens | 1 | ALA4627411 | cell-based format | Scientific Literature | |
| 16. | ALA4726252 | B | Antagonist activity at human CX3CR1 expressed in CHO-K1 cells at 20 uM by PathHunter beta-arrestin assay relative to control | Homo sapiens | 8 | ALA4725259 | cell-based format | Scientific Literature | |
| 17. | ALA4726267 | B | Antagonist activity at human CX3CR1 expressed in CHO-K1 cells by PathHunter beta-arrestin assay | Homo sapiens | 1 | ALA4725259 | cell-based format | Scientific Literature | |
| 18. | ALA4726279 | B | Agonist activity at human CX3CR1 expressed in CHO-K1 cells at 20 uM by PathHunter beta-arrestin assay relative to control | Homo sapiens | 8 | ALA4725259 | cell-based format | Scientific Literature | |
| 19. | ALA4883350 | B | PRESTO-Tango GPCRome screening (CX3CR1) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 20. | ALA5033776 | F | Agonist activity against CX3CR1 (unknown origin) assessed as induction of beta-arrestin 2 recruitment at 10 microM by beta arrestin assay relative to control | Homo sapiens | 1 | ALA5032530 | assay format | Scientific Literature |
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