| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2417101 | F | Antagonist activity at human recombinant CysLT2 receptor expressed in human HEK293 cells assessed as reduction in LTD4-induced cytosolic free Ca2+ level after 30 mins by fluorescence assay relative to control | Homo sapiens | 2 | ALA2413074 | cell-based format | Scientific Literature | |
| 2. | ALA2417103 | F | Antagonist activity at human recombinant CysLT2 receptor expressed in human HEK293 cells assessed as reduction in LTD4-induced cytosolic free Ca2+ level at 1 uM after 30 mins by fluorescence assay relative to control | Homo sapiens | 4 | ALA2413074 | cell-based format | Scientific Literature | |
| 3. | ALA2447524 | B | Inhibition of CysLT2 receptor (unknown origin) at 10 uM | Homo sapiens | 1 | ALA2440029 | single protein format | Scientific Literature | |
| 4. | ALA3266160 | B | Inhibition of human cysLTR2 at 10 uM | Homo sapiens | 1 | ALA3259772 | single protein format | Scientific Literature | |
| 5. | ALA3266166 | B | Binding affinity to cysLTR2 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3259772 | single protein format | Scientific Literature | |
| 6. | ALA3390515 | F | Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 21 | ALA3351224 | cell-based format | Scientific Literature | |
| 7. | ALA3390516 | F | Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated at 10 uM for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 2 | ALA3351224 | cell-based format | Scientific Literature | |
| 8. | ALA3404759 | F | Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated for 30 mins before LTD4 addition by Fura2-AM assay | Homo sapiens | 15 | ALA3400104 | cell-based format | Scientific Literature | |
| 9. | ALA3599261 | F | Antagonist activity at human CysLT2 expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization preincubated for 30 mins prior to LTD4 addition measured after 1 hr by Fura 2-AM dye-based fluorescence assay | Homo sapiens | 36 | ALA3596134 | cell-based format | Scientific Literature | |
| 10. | ALA3599868 | B | Antagonist activity at human CysLT2 expressed in HEK293T cells assessed as inhibition of LTC4-induced effect preincubated for 30 mins prior to LTC4 addition by Aequorin luminescence assay | Homo sapiens | 3 | ALA3596134 | cell-based format | Scientific Literature | |
| 11. | ALA3635329 | F | Agonist activity at CysLT2 receptor (unknown origin) expressed in CHO cells assessed as calcium mobilization at 3 uM | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
| 12. | ALA3635590 | F | Antagonist activity at CysLT2 receptor (unknown origin) expressed in CHO cells assessed as calcium mobilization at 3 uM | Homo sapiens | 1 | ALA3632469 | cell-based format | Scientific Literature | |
| 13. | ALA3810887 | F | Antagonist activity against CysLT2 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization pre-incubated for 10 mins before LTD4 addition by Fluo-4 AM dye based fluorimetric assay | Homo sapiens | 31 | ALA3808374 | cell-based format | Scientific Literature | |
| 14. | ALA4329868 | B | Inhibition of CysLT2 (unknown origin) | Homo sapiens | 1 | ALA4325924 | single protein format | Scientific Literature | |
| 15. | ALA4358632 | B | Activity at human CysLT2 receptor up to 10 uM | Homo sapiens | 1 | ALA4354855 | single protein format | Scientific Literature | |
| 16. | ALA4388827 | B | Displacement of [3H]LTD4 from human full-length recombinant cysteinyl leukotriene type-2 receptor expressed in HEK293 cells at 10 uM measured after 60 mins by scintillation counting method relative to control | Homo sapiens | 2 | ALA4387733 | cell-based format | Scientific Literature | |
| 17. | ALA4603372 | B | Inhibition of human CYSLt2 receptor at 10 uM relative to control | Homo sapiens | 1 | ALA4602617 | single protein format | Scientific Literature | |
| 18. | ALA4883359 | B | PRESTO-Tango GPCRome screening (CYSLTR2) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 19. | ALA5133040 | F | Antagonist activity at human CysLT2 receptor | Homo sapiens | 3 | ALA5131401 | assay format | Scientific Literature | |
| 20. | ALA5133058 | F | Agonist activity at human CysLT2 receptor | Homo sapiens | 3 | ALA5131401 | assay format | Scientific Literature |
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