| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1014657 | B | Inhibition of PLAP | 1 | ALA1139306 | single protein format | Scientific Literature | ||
| 2. | ALA3095033 | B | Inhibition of placental alkaline phosphatase (unknown origin) assessed as para nitrophenylphosphate conversion to p-nitrophenolate at pH 10.4 incubated for 10 mins prior to substrate addition measured after 5 seconds by spectrophotometric analysis | Homo sapiens | 5 | ALA3091295 | assay format | Scientific Literature | |
| 3. | ALA3095034 | B | Inhibition of placental alkaline phosphatase (unknown origin) assessed as para nitrophenylphosphate conversion to p-nitrophenolate at pH 7.8 incubated for 10 mins prior to substrate addition measured after 5 seconds by spectrophotometric analysis | Homo sapiens | 5 | ALA3091295 | assay format | Scientific Literature | |
| 4. | ALA3117348 | B | Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay | Homo sapiens | 54 | ALA3112449 | cell-based format | Scientific Literature | |
| 5. | ALA3258714 | B | Inhibition of human placenta alkaline phosphatase using p-nitrophenyl phosphate as substrate at 8.7 x 10'-5 M up to 35 mins by spectrophotometry | Homo sapiens | 3 | ALA3244014 | assay format | Scientific Literature | |
| 6. | ALA3595956 | B | Inhibition of human placental alkaline phosphatase using p-nitrophenyl phosphate substrate | Homo sapiens | 1 | ALA3593242 | assay format | Scientific Literature | |
| 7. | ALA3624979 | A | Stability assessed as human placental ALP-mediated drug degradation by measuring compound remaining level in pH 7.5 tris buffer at 10 uM incubated for 0.25 hrs by LC/MS/MS method | Homo sapiens | 1 | ALA3621120 | assay format | Scientific Literature | |
| 8. | ALA3624980 | A | Stability assessed as human placental ALP-mediated drug degradation by measuring compound remaining level in pH 7.5 tris buffer at 10 uM incubated for 0.5 hrs by LC/MS/MS method | Homo sapiens | 1 | ALA3621120 | assay format | Scientific Literature | |
| 9. | ALA3624981 | A | Stability assessed as human placental ALP-mediated drug degradation by measuring compound remaining level in pH 7.5 tris buffer at 10 uM incubated for 1 hr by LC/MS/MS method | Homo sapiens | 1 | ALA3621120 | assay format | Scientific Literature | |
| 10. | ALA3625440 | A | Stability assessed as human placental ALP-mediated drug degradation by measuring compound remaining level in pH 7.5 tris buffer at 10 uM incubated for 0.25 hrs in presence of HALT phosphatase inhibitor cocktail by LC/MS/MS method | Homo sapiens | 1 | ALA3621120 | assay format | Scientific Literature | |
| 11. | ALA3625441 | A | Stability assessed as human placental ALP-mediated drug degradation by measuring compound remaining level in pH 7.5 tris buffer at 10 uM incubated for 0.5 hrs in presence of HALT phosphatase inhibitor cocktail by LC/MS/MS method | Homo sapiens | 1 | ALA3621120 | assay format | Scientific Literature | |
| 12. | ALA3625442 | A | Stability assessed as human placental ALP-mediated drug degradation by measuring compound remaining level in pH 7.5 tris buffer at 10 uM incubated for 1 hr in presence of HALT phosphatase inhibitor cocktail by LC/MS/MS method | Homo sapiens | 1 | ALA3621120 | assay format | Scientific Literature | |
| 13. | ALA3776500 | B | Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by substrate addition | Homo sapiens | 4 | ALA3774359 | assay format | Scientific Literature | |
| 14. | ALA3776734 | B | Inhibition of human placental alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by substrate addition | Homo sapiens | 4 | ALA3774359 | assay format | Scientific Literature | |
| 15. | ALA4137340 | A | Prodrug activation assessed as human placental alkaline phosphatase mediated BMS-626529 formation | Homo sapiens | 1 | ALA4130629 | assay format | Scientific Literature | |
| 16. | ALA4137341 | A | Prodrug activation in human hepatocytes assessed as BMS-626529 formation | Homo sapiens | 1 | ALA4130629 | cell-based format | Scientific Literature | |
| 17. | ALA4186512 | B | Inhibition of PLAP (unknown origin) | Homo sapiens | 1 | ALA4184174 | single protein format | Scientific Literature | |
| 18. | ALA5152134 | B | Inhibition of PLAP (unknown origin) | Homo sapiens | 1 | ALA5150009 | single protein format | Scientific Literature | |
| 19. | ALA5152136 | B | Inhibition of human PLAP using biotinylated CDP as substrate incubated for 30 mins by chemiluminescent assay | Homo sapiens | 1 | ALA5150009 | single protein format | Scientific Literature | |
| 20. | ALA5152139 | B | Binding affinity to human PLAP incubated for 15 mins by Fluorescence polarization assay | Homo sapiens | 14 | ALA5150009 | single protein format | Scientific Literature |
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