| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA752897 | B | Inhibition of N-palmitoylethanolamine-selective acid amidase (NPAA) from rat lung homogenates at 100 uM | 14 | assay format | Scientific Literature | |||
| 2. | ALA829590 | B | Inhibitory concentration against N-palmitoylethanolamine acid amidase | 4 | single protein format | Scientific Literature | |||
| 3. | ALA831929 | B | Percent inhibition aganist N-palmitoylethanolamine acid amidase at 10 uM | 2 | single protein format | Scientific Literature | |||
| 4. | ALA2072801 | B | Inhibition of human recombinant His6-tagged NAAA expressed in HEK293 cells using 10-cis-heptadecenoylethanolamide as substrate after 30 mins by UPLC/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA2072803 | B | Non-competitive inhibition of human recombinant His6-tagged NAAA expressed in HEK293 cells using 10-cis-heptadecenoylethanolamide as substrate at 10 to 30 nM by Michaelis-Menten analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2072804 | B | Partial reversible inhibition of human recombinant His6-tagged NAAA expressed in HEK293 cells using 10-cis-heptadecenoylethanolamide as substrate at 100 nM after 30 mins by dialysis method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2072805 | B | Inhibition of human recombinant His6-tagged NAAA expressed in HEK293 cells assessed as time duration causing maximal enzyme inhibition using 10-cis-heptadecenoylethanolamide as substrate by UPLC/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2072806 | B | Binding affinity to human recombinant His6-tagged NAAA expressed in HEK293 cells assessed as formation of peptide adduct at 5 uM after 20 mins by ion chromatographic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2072807 | B | Binding affinity to human recombinant His6-tagged NAAA expressed in HEK293 cells assessed as formation of peptide adduct by MS/MS spectrophotometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1068364 | B | Inhibition of human recombinant NAAA expressed in human HEK293 cells assessed as conversion of [1,2-14C]palmitoylethanolamine to [1,2-14C]ethanolamine by liquid scintillation counting | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA1068365 | B | Inhibition of human recombinant NAAA expressed in human HEK293 cells assessed as conversion of [1,2-14C]palmitoylethanolamine to [1,2-14C]ethanolamine at 50 uM by liquid scintillation counting | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 12. | ALA1068372 | B | Competitive inhibition of human recombinant NAAA expressed in human HEK293 cells assessed as conversion of [1,2-14C]palmitoylethanolamine to [1,2-14C]ethanolamine by Lineweaver-Burke plot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA1068373 | B | Inhibition of NAAH in human intact HEK293 assessed as N-palmitoylethanolamine level by LC-APCI-MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA1068377 | B | Inhibition of NAAA | 5 | single protein format | Scientific Literature | |||
| 15. | ALA2421061 | B | Inhibition of C-terminal His-6-tagged recombinant human spleen NAAA enzyme expressed in HEK293 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA3399686 | B | Inhibition of human NAAA | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 17. | ALA3772809 | B | Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA3772811 | B | Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 50 mins by fluorescence assay | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
| 19. | ALA3772819 | B | Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addition for 30 mins by microplate reader analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3877002 | B | Competitive inhibition of recombinant human NAAA at 100 uM in presence of varying levels of PAMCA as substrate preincubated for 30 mins followed by substrate addition measured every 3 mins for 2.5 hrs by Lineweaver-Burk plot analysis | Homo sapiens | 4 | single protein format | Scientific Literature |
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