# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA677513 | B | Inhibitory concentration against Enzymatic A chain of ricin (RTA) using Artemia salina ribosomes | Ricinus communis | 12 | ALA1135433 | single protein format | Scientific Literature | |
2. | ALA1826784 | B | Inhibition of castor seed ricin A chain translation degradation activity in rabbit reticulocyte lysate after 90 mins by luciferase-based luminometer analysis | Ricinus communis | 10 | ALA1821685 | assay format | Scientific Literature | |
3. | ALA1826785 | B | Inhibition of castor seed ricin A chain translation degradation activity in rabbit reticulocyte lysate at maximum concentration after 90 mins by luciferase-based luminometer analysis | Ricinus communis | 5 | ALA1821685 | assay format | Scientific Literature | |
4. | ALA1826786 | B | Binding affinity to castor seed ricin A chain in rabbit reticulocyte lysate assessed as change in melting temperature at 500 uM after 30 mins by differential scanning calorimetry | Ricinus communis | 12 | ALA1821685 | assay format | Scientific Literature | |
5. | ALA2090455 | B | Inhibition of Ricinus communis ricin toxin A after 90 mins by luciferase reporter gene assay | Ricinus communis | 16 | ALA2086349 | single protein format | Scientific Literature | |
6. | ALA2090456 | B | Ratio of 7-carboxypterin IC50 to compound IC50 for Ricinus communis ricin toxin A | Ricinus communis | 1 | ALA2086349 | single protein format | Scientific Literature | |
7. | ALA2320360 | B | Inhibition of Ricin toxin A after 90 mins by luciferase-translational assay | Ricinus communis | 15 | ALA2311277 | single protein format | Scientific Literature | |
8. | ALA2320361 | B | Inhibition of Ricin toxin A | Ricinus communis | 1 | ALA2311277 | single protein format | Scientific Literature | |
9. | ALA3101399 | B | Inhibition of castor bean ricin toxin A after 90 mins by luciferase reporter gene assay | Ricinus communis | 14 | ALA3098027 | single protein format | Scientific Literature | |
10. | ALA3111133 | B | Inhibition of castor bean ricin-induced toxicity in human A549 cells assessed as protection against toxin-induced inhibition of protein biosynthesis by measuring incorporation of [14C]-leucine into cells at 30 uM preincubated for 1 hr followed by toxin challenge measured after 20 hrs by liquid scintillation counting analysis relative to control | Ricinus communis | 2 | ALA3108768 | cell-based format | Scientific Literature | |
11. | ALA3111135 | B | Inhibition of castor bean ricin-induced toxicity in human A549 cells assessed as protection against toxin-induced inhibition of protein biosynthesis by measuring incorporation of [14C]-leucine into cells preincubated for 1 hr followed by toxin challenge measured after 20 hrs by liquid scintillation counting analysis | Ricinus communis | 3 | ALA3108768 | cell-based format | Scientific Literature | |
12. | ALA5032049 | B | Binding affinity to castor beans ricin toxin A subunit assessed as dissociation constant | Ricinus communis | 1 | ALA5030555 | single protein format | Scientific Literature | |
13. | ALA5032050 | B | Inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using liver ribosomes by qRT-PCR analysis | Ricinus communis | 1 | ALA5030555 | assay format | Scientific Literature | |
14. | ALA5032051 | B | Inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes at 100 uM by qRT-PCR analysis | Ricinus communis | 14 | ALA5030555 | single protein format | Scientific Literature | |
15. | ALA5032052 | B | Binding affinity to castor beans ricin toxin A subunit assessed as dissociation constant by surface plasmon resonance analysis | Ricinus communis | 14 | ALA5030555 | single protein format | Scientific Literature | |
16. | ALA5032053 | B | Potency index, ratio of CC10501 to test compound IC50 for inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes by qRT-PCR analysis | Ricinus communis | 4 | ALA5030555 | single protein format | Scientific Literature | |
17. | ALA5032054 | B | Inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes by qRT-PCR analysis | Ricinus communis | 5 | ALA5030555 | single protein format | Scientific Literature | |
18. | ALA5032055 | B | Maximal inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes by qRT-PCR analysis | Ricinus communis | 4 | ALA5030555 | single protein format | Scientific Literature | |
19. | ALA5032056 | B | Inhibition of castor bean ricin mediated depurination activity African green monkey Vero cells toxin pretreated for 2 hrs at 250 uM measured after 2 hrs of cell addition by qRT-PCR analysis | Ricinus communis | 5 | ALA5030555 | cell-based format | Scientific Literature | |
20. | ALA5032057 | B | Inhibition of castor bean ricin mediated depurination activity African green monkey Vero cells toxin pretreated for 2 hrs at 500 uM measured after 2 hrs of cell addition by qRT-PCR analysis | Ricinus communis | 5 | ALA5030555 | cell-based format | Scientific Literature |