# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3816448 | Binding | Induction of degradation of halo-tagged c-jun (unknown origin) expressed in HEK293 cells assessed as time required to reduce level of halo-tagged c-jun at 10 uM by Western blot analysis | Homo sapiens | 4 | ALA3813609 | cell-based format | Scientific Literature | |
2. | ALA645946 | Binding | Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cells | 24 | ALA1133475 | cell-based format | Scientific Literature | ||
3. | ALA902315 | Binding | Inhibition of c-Jun phosphorylation in HepG2 cells | Homo sapiens | 1 | ALA1138387 | cell-based format | Scientific Literature | |
4. | ALA886374 | Binding | Inhibition of cJun translocation in IL-1-beta-stimulated A549 cells | Homo sapiens | 24 | ALA1139954 | cell-based format | Scientific Literature | |
5. | ALA888216 | Binding | Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assay | Homo sapiens | 10 | ALA1140007 | cell-based format | Scientific Literature | |
6. | ALA1105366 | Binding | Inhibition of AP-1 expressed in HEK293 cells assessed as PMA-stimulated transcriptional activation at 10 uM treated 24 hrs before PMA challenge measured after 20 to 24 hrs by luciferase reporter gene assay | 37 | ALA1156197 | cell-based format | Scientific Literature | ||
7. | ALA1106185 | Binding | Inhibition of AP-1 expressed in HEK293 cells assessed as PMA-stimulated transcriptional activation at 1 uM treated 24 hrs before PMA challenge measured after 20 to 24 hrs by luciferase reporter gene assay | 37 | ALA1156197 | cell-based format | Scientific Literature | ||
8. | ALA1106187 | Binding | Inhibition of AP-1 expressed in HEK293 cells assessed as PMA-stimulated transcriptional activation treated 24 hrs before PMA challenge measured after 20 to 24 hrs by luciferase reporter gene assay | 7 | ALA1156197 | cell-based format | Scientific Literature | ||
9. | ALA1176655 | Binding | Inhibition of transcriptional activity of AP1 transfected in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay | 4 | ALA1177640 | cell-based format | Scientific Literature | ||
10. | ALA1226568 | Binding | Activation of c-Jun expressed in HEK293 cells assessed as induction of protein interaction with Pin1 by EYFP based reporter gene assay | 4 | ALA1221184 | cell-based format | Scientific Literature | ||
11. | ALA1226578 | Binding | Inhibition of of c-Jun expressed in HEK293 cells assessed as induction of protein interaction in presence of camptothecin with Pin1 by EYFP based reporter gene assay | 7 | ALA1221184 | cell-based format | Scientific Literature | ||
12. | ALA1243707 | Binding | Binding affinity to wild-type c-Jun homodimer at by circular dichroism spectroscopy | 1 | ALA1240333 | single protein format | Scientific Literature | ||
13. | ALA1243710 | Binding | Binding affinity to c-Jun homodimer containing bipartite tetracysteine motif at 25 nM | 1 | ALA1240333 | single protein format | Scientific Literature | ||
14. | ALA1243714 | Binding | Binding affinity to c-Jun homodimer containing bipartite tetracysteine motif at 100 nM | 1 | ALA1240333 | single protein format | Scientific Literature | ||
15. | ALA1243723 | Binding | Binding affinity to wild type c-Jun homodimer by circular dichroism spectroscopy | 1 | ALA1240333 | single protein format | Scientific Literature | ||
16. | ALA1243732 | Binding | Binding affinity to c-Jun homodimer containing bipartite tetracycline motif | 1 | ALA1240333 | single protein format | Scientific Literature | ||
17. | ALA1249117 | Binding | Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation at 1 uM treated 24 hrs before PMA challenge by luciferase reporter gene assay relative to control | 18 | ALA1240423 | cell-based format | Scientific Literature | ||
18. | ALA1249120 | Binding | Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of PMA-induced transcriptional activation treated 24 hrs before PMA challenge by luciferase reporter gene assay | 7 | ALA1240423 | cell-based format | Scientific Literature | ||
19. | ALA1763333 | Binding | Inhibition of c-Jun | 31 | ALA1759990 | single protein format | Scientific Literature | ||
20. | ALA1769966 | Binding | Inhibition of TPA-induced AP-1 activation in cells expressing beta-lactamase after 18 hrs using FRET substrate by cell-based high-throughput screening assay | 2 | ALA1765002 | cell-based format | Scientific Literature |