# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA618425 | Binding | Inhibition of protein biosynthesis at the level of the peptidyl transferase center of the 50 s ribosomal subunit | 1 | ALA1152004 | subcellular format | Scientific Literature | ||
2. | ALA1696641 | Binding | Inhibition of mammalian ribosomal activity by coupled transcription/translation assay | 2 | ALA1687722 | subcellular format | Scientific Literature | ||
3. | ALA828548 | Binding | Inhibition of bacterial translation by blocking the function of the ribosomal GTPase center | Escherichia coli | 1 | ALA1139553 | subcellular format | Scientific Literature | |
4. | ALA834026 | Binding | Inhibition of bacterial translation by blocking the function of the ribosomal GTPase center at 15 uM concentration | Escherichia coli | 1 | ALA1139553 | subcellular format | Scientific Literature | |
5. | ALA834030 | Binding | Inhibition of bacterial translation by blocking the function of the ribosomal GTPase center at 150 uM concentration | Escherichia coli | 3 | ALA1139553 | subcellular format | Scientific Literature | |
6. | ALA834031 | Binding | Inhibition of bacterial translation by blocking the function of the ribosomal GTPase center at 400 uM concentration | Escherichia coli | 7 | ALA1139553 | subcellular format | Scientific Literature | |
7. | ALA836111 | Binding | Inhibition of bacterial translation by blocking the function of the ribosomal GTPase center at 0.17 uM concentration | Escherichia coli | 1 | ALA1139553 | subcellular format | Scientific Literature | |
8. | ALA1169090 | Binding | Induction of ribosome to readthrough in-frame renilla/firefly TGA codon transfected in rabbit reticulocyte at 200 to 600 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 3 | ALA1165913 | subcellular format | Scientific Literature | |
9. | ALA1169091 | Binding | Induction of ribosome to readthrough in-frame renilla/firefly TGA codon transfected in rabbit reticulocyte at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
10. | ALA1169092 | Binding | Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly PCDH15 R3X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
11. | ALA1166118 | Binding | Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly PCDH15 R245X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
12. | ALA1166119 | Binding | Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly CFTR G542X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
13. | ALA1166120 | Binding | Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly CFTR W1282X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
14. | ALA1166121 | Binding | Induction of ribosome to readthrough in-frame UGA codon associated with renilla/firefly dystrophin R3381X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
15. | ALA1166122 | Binding | Induction of ribosome to readthrough in-frame UAG codon of renilla/firefly IDUA Q70X nonsense mutant gene transfected in rabbit reticulocyte assessed as reduction in overall translation at 5 to 20 uM after 16 hrs dual-luciferase reporter gene assay | Oryctolagus cuniculus | 4 | ALA1165913 | subcellular format | Scientific Literature | |
16. | ALA1166123 | Binding | Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly PCDH15 R3X nonsense mutant gene transfected in HEK293 cells assessed as reduction in overall translation at 1 to 2 mM after 6 hrs dual-luciferase reporter gene assay | Homo sapiens | 2 | ALA1165913 | subcellular format | Scientific Literature | |
17. | ALA1166124 | Binding | Induction of ribosome to readthrough in-frame UAG codon of renilla/firefly IDUA Q70X nonsense mutant gene transfected in HEK293 cells assessed as reduction in overall translation at 1 to 2 mM after 6 hrs dual-luciferase reporter gene assay | Homo sapiens | 2 | ALA1165913 | subcellular format | Scientific Literature | |
18. | ALA1166125 | Binding | Induction of ribosome to readthrough in-frame UGA codon of renilla/firefly CFTR W1282X nonsense mutant gene transfected in HEK293 cells assessed as reduction in overall translation at 1 to 2 mM after 6 hrs dual-luciferase reporter gene assay | Homo sapiens | 2 | ALA1165913 | subcellular format | Scientific Literature | |
19. | ALA1639014 | Binding | Inhibition of ribosome peptidyl transferase site in rabbit reticulocytes assessed as inhibition of translation using firefly luciferase DNA as template at 0.8 to 80 uM after 1 hr by luciferase assay | Oryctolagus cuniculus | 1 | ALA1629688 | subcellular format | Scientific Literature | |
20. | ALA1638699 | Binding | Binding affinity to ribosome in reticulocyte lysate assessed as inhibition of transcription-translational activity by luciferase assay | 9 | ALA1629423 | subcellular format | Scientific Literature |