# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA859597 | F | Activity at rat TAAR1 by measuring cAMP accumulation in HEK293 cells | Rattus norvegicus | 38 | ALA1149397 | cell-based format | Scientific Literature | |
2. | ALA905018 | F | Activity at rat TAAR1 expressed in HEK293 cells assessed as cAMP production | Rattus norvegicus | 27 | ALA1143684 | cell-based format | Scientific Literature | |
3. | ALA905019 | F | Efficacy at rat TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production at 10 uM relative to 3-iodothyronamine | Rattus norvegicus | 27 | ALA1143684 | cell-based format | Scientific Literature | |
4. | ALA956566 | F | Agonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level at <=10 uM after 1 hr | Rattus norvegicus | 4 | ALA1151799 | cell-based format | Scientific Literature | |
5. | ALA958999 | F | Agonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level | Rattus norvegicus | 1 | ALA1151799 | cell-based format | Scientific Literature | |
6. | ALA959000 | F | Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level at 10 uM after 1 hr | Rattus norvegicus | 5 | ALA1151799 | cell-based format | Scientific Literature | |
7. | ALA959001 | F | Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP level | Rattus norvegicus | 5 | ALA1151799 | cell-based format | Scientific Literature | |
8. | ALA1670084 | B | Inhibition of rat TAAR1 | Rattus norvegicus | 2 | ALA1667822 | single protein format | Scientific Literature | |
9. | ALA1670130 | F | Antagonist activity at rat TAAR1 assessed as reversal of endogenous beta-PEA effect | Rattus norvegicus | 1 | ALA1667822 | assay format | Scientific Literature | |
10. | ALA1930652 | F | Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation counting | Rattus norvegicus | 6 | ALA1926662 | cell-based format | Scientific Literature | |
11. | ALA1930653 | F | Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by competitive binding assay | Rattus norvegicus | 4 | ALA1926662 | cell-based format | Scientific Literature | |
12. | ALA1930654 | F | Activation of rat TAAR1 expressed in Syrian hamster AV12-664 cells assessed as accumulation of cAMP after 30 mins using cAMP XS EA/CL as substrate by luminescence method | Rattus norvegicus | 4 | ALA1926662 | cell-based format | Scientific Literature | |
13. | ALA2213507 | F | Agonist activity at rat TAAR1 receptor expressed in HEK293 cells after 30 mins | Rattus norvegicus | 6 | ALA2203234 | cell-based format | Scientific Literature | |
14. | ALA2215955 | F | Agonist activity at rat TAAR1 receptor expressed in HEK293 cells after 30 mins relative to control | Rattus norvegicus | 6 | ALA2203234 | cell-based format | Scientific Literature | |
15. | ALA3112131 | F | Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production at at 0.0001 to 100 uM after 1 hr by chemiluminescent assay relative to control | Rattus norvegicus | 1 | ALA3108730 | cell-based format | Scientific Literature | |
16. | ALA3112133 | F | Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production at at 0.0001 to 100 uM after 1 hr by chemiluminescent assay relative to control | Rattus norvegicus | 1 | ALA3108730 | cell-based format | Scientific Literature | |
17. | ALA3112135 | F | Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production at at 0.0001 to 100 uM after 1 hr by chemiluminescent assay relative to control | Rattus norvegicus | 1 | ALA3108730 | cell-based format | Scientific Literature | |
18. | ALA3110484 | F | Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production at at 0.0001 to 100 uM after 1 hr by chemiluminescent assay relative to beta-phenylethylamine | Rattus norvegicus | 4 | ALA3108730 | cell-based format | Scientific Literature | |
19. | ALA3110486 | F | Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production at at 0.0001 to 100 uM after 1 hr by chemiluminescent assay relative to beta-phenylethylamine | Rattus norvegicus | 4 | ALA3108730 | cell-based format | Scientific Literature | |
20. | ALA3110488 | F | Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production at at 0.0001 to 100 uM after 1 hr by chemiluminescent assay relative to beta-phenylethylamine | Rattus norvegicus | 4 | ALA3108730 | cell-based format | Scientific Literature |