# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3428949 | Functional | Agonist activity at human GPR40 expressed in CHO cells assessed as calcium flux by FLIPR assay | Homo sapiens | 16 | ALA3425426 | cell-based format | Scientific Literature | |
2. | ALA3602370 | Functional | Agonist activity at GPR40 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin | Homo sapiens | 29 | ALA3600322 | cell-based format | Scientific Literature | |
3. | ALA3602371 | Functional | Agonist activity at GPR40 (unknown origin) expressed in CHO cells at 5 uM by FLIPR calcium flux assay relative to GW9508 | Homo sapiens | 28 | ALA3600322 | cell-based format | Scientific Literature | |
4. | ALA3607676 | Functional | Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level after 60 mins by FLIPR assay | Homo sapiens | 56 | ALA3603738 | cell-based format | Scientific Literature | |
5. | ALA3619103 | Functional | Agonist activity at human FFA1 expressed in CHO cells assessed as induction of receptor activation by measuring Ca2+influx at 300 nM incubated for by FLIPR method | Homo sapiens | 13 | ALA3616472 | cell-based format | Scientific Literature | |
6. | ALA3619605 | Functional | Agonist activity at human FFA1 expressed in CHO cells assessed as induction of receptor activation by measuring Ca2+influx at 100 nM incubated for by FLIPR method | Homo sapiens | 37 | ALA3616472 | cell-based format | Scientific Literature | |
7. | ALA3619606 | Functional | Agonist activity at human FFA1 expressed in CHO cells assessed as induction of receptor activation by measuring Ca2+influx incubated for by FLIPR method | Homo sapiens | 27 | ALA3616472 | cell-based format | Scientific Literature | |
8. | ALA3632222 | Functional | Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux at 100 nM by FLIPR assay relative to control | Homo sapiens | 22 | ALA3627655 | cell-based format | Scientific Literature | |
9. | ALA3632223 | Functional | Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by FLIPR assay | Homo sapiens | 22 | ALA3627655 | cell-based format | Scientific Literature | |
10. | ALA3744105 | Functional | Antagonist activity against human GPR40 expressed in HEK293s FLPIN cells assessed as elaidic acid stimulated IP1 release after 2 hrs by TR-FRET analysis | Homo sapiens | 47 | ALA3739339 | cell-based format | Scientific Literature | |
11. | ALA3755625 | Binding | Partial agonist activity at human GPR40 expressed in CHO cells measured over 20 secs interval by luminometric analysis | Homo sapiens | 9 | ALA3751835 | cell-based format | Scientific Literature | |
12. | ALA3755626 | Binding | Partial agonist activity at human GPR40 expressed in CHO cells measured over 20 secs interval by luminometric analysis in presence of 0.01% human serum albumin | Homo sapiens | 18 | ALA3751835 | cell-based format | Scientific Literature | |
13. | ALA3756705 | Binding | Partial agonist activity at human GPR40 expressed in CHO cells measured over 20 secs interval by luminometric analysis in presence of 100% human serum | Homo sapiens | 18 | ALA3751835 | cell-based format | Scientific Literature | |
14. | ALA3756907 | Binding | Potency index , ratio of EC50 for AMG837 to EC50 for test compound for partial agonist activity at human GPR40 expressed in CHO cells measured over 20 secs interval by luminometric analysis in presence of 0.01% human serum albumin | Homo sapiens | 2 | ALA3751835 | cell-based format | Scientific Literature | |
15. | ALA3760345 | Functional | Agonist activity at human FFAR1 expressed in CHO-K1 cells assessed as calcium flux measured for 100 secs by FLIPR assay | Homo sapiens | 16 | ALA3758151 | cell-based format | Scientific Literature | |
16. | ALA3760347 | Functional | Partial agonist activity at human GPR40 expressed in CHO cells assessed as fatty acid-induced calcium mobilization by FLIPR assay | Homo sapiens | 1 | ALA3758151 | cell-based format | Scientific Literature | |
17. | ALA3760348 | Binding | Modulation of FFAR1 (unknown origin) | Homo sapiens | 2 | ALA3758151 | single protein format | Scientific Literature | |
18. | ALA3767643 | Functional | Partial agonist activity at human free fatty acid receptor 1 expressed in HEK293 cells assessed as inositol phosphate 1 accumulation incubated for 30 mins | Homo sapiens | 1 | ALA3763124 | cell-based format | Scientific Literature | |
19. | ALA3783039 | Functional | Agonist activity at human FFA1 expressed in CHO cells assessed as intracellular Ca2+ level at 300 nM measured for 90 secs by Fluo-4 AM-based FLIPR assay | Homo sapiens | 9 | ALA3779832 | cell-based format | Scientific Literature | |
20. | ALA3783040 | Functional | Agonist activity at human FFA1 expressed in CHO cells assessed as intracellular Ca2+ level at 100 nM measured for 90 secs by Fluo-4 AM-based FLIPR assay | Homo sapiens | 14 | ALA3779832 | cell-based format | Scientific Literature |