| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA860704 | B | Displacement of [125I]MIP-3beta from CCR7 expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA870796 | B | Inhibition of CCR7 expressed in CHO cells at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA928587 | B | Inhibition of CCR7 upto 1 uM | 1 | single protein format | Scientific Literature | |||
| 4. | ALA923002 | B | Binding affinity to CCR7 receptor | 1 | single protein format | Scientific Literature | |||
| 5. | ALA958164 | B | Inhibition of CCR7 | 1 | single protein format | Scientific Literature | |||
| 6. | ALA1070559 | F | Agonist activity at CCR7 up to 30 uM | 1 | assay format | Scientific Literature | |||
| 7. | ALA2328029 | B | Antagonist activity at CCR7 (unknown origin) assessed as inhibition of chemotaxis at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2328622 | F | Antagonist activity at CCR7 (unknown origin) assessed as inhibition of calcium flux at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2328643 | B | Binding affinity to CCR7 (unknown origin) at 10 uM by radioligand displacement assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3097211 | B | Inhibition of CCR7 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2439716 | F | Antagonist activity at CCR7 in human CCRF-CEM cells assessed as inhibition of MIP-3beta-induced calcium flux at 5 uM preincubated for 15 mins by spectrophotometric analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 12. | ALA5251596 | B | Binding affinity to CCR7 (unknown origin) at 10 uM by radioligand binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4028340 | F | Antagonist activity at human CCR7 expressed in CHOK1 cells assessed as inhibition of CCL19-induced cAMP accumulation at 10 uM preincubated for 30 mins followed agonist addition measured after 30 to 60 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4037565 | B | Agonist activity at CCR7 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4037583 | B | Antagonist activity at CCR7 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4134313 | F | Antagonist activity at CCR7 (unknown origin) at 10 uM | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 17. | ALA4235803 | F | Inhibition of human CCR7 expressed in CHO cells assessed as decrease in CCL19-induced reduction of forskolin-stimulated cAMP accumulation preincubated for 30 mins followed agonist addition measured after 30 mins by HTRF assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA4344296 | B | Inhibition of CCR7 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 19. | ALA4630474 | B | Antagonist activity at human Gi/G0-coupled CCR7 receptor assessed as inhibition of CCL19-induced beta arrestin2 recruitment at 500 nM preincubated for 30 mins followed by CCL19 stimulation and measured after 90 to 180 mins by pathhunter assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4845529 | F | Antagonist activity at CCR7 (unknown origin) assessed as inhibition of ligand-induced calcium flux measured upto 10 uM | Homo sapiens | 1 | assay format | Scientific Literature |
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