# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA862793 | B | Activity at LPA1 receptor in RH7777 rat hepatoma cell line | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
2. | ALA862797 | B | Activity at LPA1 receptor in RH7777 rat hepatoma cell line at 30 uM | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
3. | ALA903636 | F | Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium influx | Rattus norvegicus | 12 | cell-based format | Scientific Literature | ||
4. | ALA4144011 | F | Antagonist activity at LPA1 in CD(SD)IGS rat urethra assessed as inhibition of LPA-induced urethra contraction at 1 uM pretreated for 30 mins followed by LPA addition | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
5. | ALA4144012 | F | Antagonist activity at LPA1 in CD(SD)IGS rat urethra assessed as inhibition of LPA-induced urethra contraction at 1 uM pretreated for 30 mins prior to LPA addition followed by compound washout every 10 minutes for 2 times and subsequent LPA stimulation | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
6. | ALA4610724 | F | Agonist activity at LPA1 receptors in Wistar rat DRG neurons assessed as increase in calcium influx at 10 uM measured after 10 secs in presence of capsaicin by Fluo-4 NW dye based inverted microscopic method | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
7. | ALA4610725 | F | Agonist activity at LPA1 receptors in Wistar rat DRG neurons assessed as increase in calcium influx at 500 nM measured after 10 secs in presence of capsaicin by Fluo-4 NW dye based inverted microscopic method | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
8. | ALA4610726 | F | Induction of LPA1 receptor desensitization in Wistar rat DRG neurons assessed as reduction in calcium influx at 10 uM treated twice after 10 secs in presence of capsaicin by Fluo-4 NW dye based inverted microscopic method | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
9. | ALA4610727 | B | Agonist activity at LPA1 receptors in Wistar rat DRG neurons assessed as increase in neuronal activity at 10 uM incubated for 15 secs in presence of capsaicin by Microelectrode Array | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
10. | ALA4610728 | B | Induction of LPA1 receptor desensitization in Wistar rat DRG neurons assessed as reduction in neuronal activity at 10 uM treated for 15 secs twice with 4 mins interval in presence of capsaicin by microelectrode Array | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
11. | ALA4610735 | B | Agonist activity at LPA1 receptors in Wistar rat DRG neurons assessed as increase in neuronal activity at 10 uM incubated for 15 secs in presence of capsazepine by Microelectrode Array | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
12. | ALA4610736 | B | Induction of LPA1 receptor desensitization in Wistar rat DRG neurons assessed as reduction in neuronal activity at 10 uM treated for 15 secs twice with 4 mins interval in presence of capsazepine by microelectrode Array | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
13. | ALA4827707 | B | Inhibition of LPA in rat plasma after 18 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | cell-free format | Scientific Literature |