| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA867801 | B | Displacement of [125I]I309 from human CCR8 expressed in L1.2 cells | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA867802 | F | Inhibition of I309-induced chemotaxis in L1.2 cells expressing CCR8 | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA863696 | B | Binding affinity to CCR8 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA855860 | B | Inhibition of CCR8 at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA855762 | B | Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assay | Homo sapiens | 60 | cell-based format | Scientific Literature | ||
| 6. | ALA855766 | F | Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FLIPR assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 7. | ALA903462 | F | Antagonist activity at human recombinant CCR8 expressed in RBL cells assessed as inhibition of I-309-induced intracellular calcium mobilization by FLIPR assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 8. | ALA903461 | F | Antagonist activity at human recombinant CCR8 expressed in HUT78 cells assessed as I309-mediated migration by chemotaxis assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA902420 | F | Antagonist activity at human recombinant CCR8 expressed in Th2 cells assessed as I309 mediated migration by chemotaxis assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA923003 | B | Binding affinity to CCR8 receptor | 1 | single protein format | Scientific Literature | |||
| 11. | ALA948147 | F | Antagonist activity at CCR8 receptor | 14 | assay format | Scientific Literature | |||
| 12. | ALA1045844 | F | Antagonist activity at human CCR8 | Homo sapiens | 30 | assay format | Scientific Literature | ||
| 13. | ALA2039639 | B | Inhibition of human CCR8 by FLIPR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA2215082 | F | Allosteric modulation at human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation counting analysis relative to basal level | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 15. | ALA2215083 | F | Ratio of ZnPhe EC50 to compound EC50 for human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 16. | ALA2215084 | F | Ratio of ZnBip EC50 to compound EC50 for human CCR8 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA2215086 | F | Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 18. | ALA2328030 | B | Antagonist activity at CCR8 (unknown origin) assessed as inhibition of chemotaxis at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA2328621 | F | Antagonist activity at CCR8 (unknown origin) assessed as inhibition of calcium flux at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA2328642 | B | Binding affinity to CCR8 (unknown origin) at 10 uM by radioligand displacement assay | Homo sapiens | 1 | single protein format | Scientific Literature |
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