| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA860700 | B | Inhibition of human serine racemase at 2 mM | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 2. | ALA860701 | B | Inhibition of human serine racemase | Microsporidium prosopium | 2 | single protein format | Scientific Literature | ||
| 3. | ALA1042556 | B | Inhibition of human recombinant serine racemase assessed as formation of D-serine at 5 mM in phosphate buffer of pH 8 treated for 15 to 20 mins before addition of substrate by HPLC analysis in presence of 10 uM PLP | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA1042561 | B | Inhibition of human recombinant serine racemase assessed as formation of D-serine at 5 mM treated for 15 to 20 mins before addition of substrate by HPLC analysis in presence of increasing concentration of PLP | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA2327930 | B | Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mins by fluorescence assay | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 6. | ALA3380621 | B | Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production after 10 mins by Saccharomyces cerevisiae Dsd1SC based D-serine detection assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 7. | ALA3380622 | B | Inhibition of full length human recombinant serine recemase C2DC6D mutant expressed in Escherichia coli BL21 (DE3) assessed as D-serine production at 1 mM after 10 mins by Saccharomyces cerevisiae Dsd1SC based D-serine detection assay | Homo sapiens | 38 | assay format | Scientific Literature | ||
| 8. | ALA3363335 | B | Binding affinity to serine recemase (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA3619158 | B | Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as reduction in beta-elimination of L-serine at 5 mM by spectrophotomtery | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA3619159 | B | Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as reduction in beta-elimination of L-serine at 2.8 mM by spectrophotomtery | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3619160 | B | Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as reduction in beta-elimination of L-serine at 1.2 mM by spectrophotomtery | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3619161 | B | Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as reduction in beta-elimination of L-serine at 330 uM by spectrophotomtery | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3619307 | B | Inhibition of hexa-His-tagged purified human recombinant serine racemase expressed in Escherichia coli BL21 Codonplus (DE3)-RIL cells assessed as reduction in beta-elimination of L-serine at by spectrophotomtery | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA3619308 | B | Inhibition of human recombinant serine racemase expressed in Escherichia coli Rosetta 2 (DE3) cells using L-serine as substrate by horseradish peroxidase based couple assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4184695 | B | Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level at 1 mM using Dsd1 as substrate and PLP as co-factor pretreated for 30 mins followed by substrate and co-factor addition measured after 30 mins relative to control | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 16. | ALA4184696 | B | Inhibition of wild-type serine racemase (unknown origin) assessed as residual activity by measuring D-serine level using Dsd1 as substrate and PLP as co-factor pretreated for 30 mins followed by substrate and co-factor addition measured after 30 mins | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 17. | ALA4184697 | B | Inhibition of serine racemase mutant (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4418367 | B | Inhibition of recombinant human SRR expressed in Escherichia coli assessed as reduction in conversion of L-serine to D-serine at 1 mM incubated for => 8 hrs in presence of PLP and recombinant D-serine dehydratase 1 by spectrophotometry relative to control | Homo sapiens | 62 | assay format | Patent Bioactivity Data | ||
| 19. | ALA4418368 | B | Inhibition of recombinant human SRR expressed in Escherichia coli assessed as reduction in conversion of L-serine to D-serine at 0.1 mM incubated for => 8 hrs in presence of PLP and recombinant D-serine dehydratase 1 by spectrophotometry relative to control | Homo sapiens | 39 | assay format | Patent Bioactivity Data | ||
| 20. | ALA4418369 | B | Inhibition of recombinant human SRR expressed in Escherichia coli assessed as reduction in conversion of L-serine to D-serine at 0.3 mM incubated for => 8 hrs in presence of PLP and recombinant D-serine dehydratase 1 by spectrophotometry relative to control | Homo sapiens | 5 | assay format | Patent Bioactivity Data |
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