| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA859689 | B | Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 2. | ALA859693 | B | Inhibitory activity against human SIRT1 by radiochemical Nicotinamide release assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA859800 | B | Inhibitory activity against human SIRT1 at 100 uM | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 4. | ALA859743 | B | Inhibitory activity against human SIRT1 | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 5. | ALA868535 | B | Inhibition of human SIRT1 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA868536 | B | Inhibition of human SIRT1 at 2 mM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA908191 | B | Inhibition of human SIRT1 | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 8. | ALA908190 | B | Inhibition of human SIRT1 at 50 uM | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 9. | ALA908188 | B | Inhibition of human SIRT1 by fluorescent deacetylase assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 10. | ALA909828 | B | Inhibition of human SIRT1 by radioactive deacetylase assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA1814969 | B | Inhibition of SIRT1 | 28 | single protein format | Scientific Literature | |||
| 12. | ALA2072664 | B | Activation of SIRT1 expressed in HEK293 cells assessed as increase in enzyme deacetylation activity at 10 uM using acetylated p53 substrate and NAD+ by bioluminescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA2072719 | B | Activation of SIRT1 expressed in HEK293 cells assessed as reduction in p53 transcriptional activity at 10 uM incubated for 12 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA2072720 | B | Activation of SIRT1 expressed in HEK293 cells assessed as increase in enzyme deacetylation activity pre-incubated for 10 mins before addition of acetylated p53 peptide substrate and NAD+ by NAD+/NADH assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA2072721 | B | Activation of SIRT1 expressed in HEK293 cells assessed as reduction in p53 transcriptional activity incubated for 12 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA2072722 | B | Activation of SIRT1 expressed in HEK293 cells assessed as increase in NAD to NADH ratio at 20 uM pre-incubated for 10 mins before addition of acetylated p53 peptide substrate and NAD+ by NAD+/NADH assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA1799832 | B | Inhibition of human recombinant SIRT1 expressed in Escherichia coli incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 18. | ALA1799834 | B | Inhibition of human recombinant SIRT1 expressed in Escherichia coli at 50 uM incubated at 37 degC for 2 hrs by Fluor de Lys fluorescence assay | Homo sapiens | 39 | assay format | Scientific Literature | ||
| 19. | ALA1799838 | B | Inhibition of human recombinant GST-tagged SIRT1 using acetylated HeLa histones substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA1799840 | B | Inhibition of human recombinant GST-tagged SIRT1 expressed in 293T cells by Fluor de Lys fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!