| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA866499 | B | Binding affinity to choline transporter at 10 uM | 1 | ALA1138125 | single protein format | Scientific Literature | ||
| 2. | ALA1015805 | B | Inhibition of choline transporter at 10 uM | 1 | ALA1136869 | single protein format | Scientific Literature | ||
| 3. | ALA1248888 | B | Binding affinity to human choline transporter (CHT1) by radioligand displacement assay | Homo sapiens | 2 | ALA1240489 | single protein format | Scientific Literature | |
| 4. | ALA1794362 | F | PUBCHEM_BIOASSAY: Dose responses of compounds that inhibit the Choline Transporter (CHT) - 5 point CRC. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488975, AID488997, AID493221, AID493222] | 896 | ALA1201862 | assay format | PubChem BioAssays | ||
| 5. | ALA1794546 | F | PUBCHEM_BIOASSAY: Dose responses of compounds that inhibit the Choline Transporter (CHT) - 10 point CRC. (Class of assay: confirmatory) | 274 | ALA1201862 | assay format | PubChem BioAssays | ||
| 6. | ALA1964033 | F | PUBCHEM_BIOASSAY: Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC. (Class of assay: confirmatory) | 60 | ALA1201862 | assay format | PubChem BioAssays | ||
| 7. | ALA1963920 | F | PUBCHEM_BIOASSAY: JHICC_CHT_Inh_3H uptake_CRC. (Class of assay: confirmatory) | 14 | ALA1201862 | assay format | PubChem BioAssays | ||
| 8. | ALA2114879 | F | PubChem BioAssay. Dose responses of compounds that activate the Choline Transporter (CHT) in a 3H-choline uptake radioactive assay. (Class of assay: confirmatory) | Homo sapiens | ⋯ | ALA1201862 | assay format | PubChem BioAssays | |
| 9. | ALA2114838 | F | PubChem BioAssay. Dose responses of compounds that inhibit the Choline Transporter (CHT) in a 3H-choline uptake radioactive assay. (Class of assay: confirmatory) | Homo sapiens | 1 | ALA1201862 | assay format | PubChem BioAssays | |
| 10. | ALA2208514 | F | Antagonist activity at CHT1 | 1 | ALA2203227 | assay format | Scientific Literature | ||
| 11. | ALA3215100 | F | PubChem BioAssay. Discovery and structure-activity relationship of a novel choline transporter inhibitor. (Class of assay: confirmatory) | 13 | ALA1201862 | assay format | PubChem BioAssays | ||
| 12. | ALA3215119 | F | PubChem BioAssay. Discovery and structure-activity relationship of a novel choline transporter inhibitor, Selectivity Studies. (Class of assay: confirmatory) | 72 | ALA1201862 | assay format | PubChem BioAssays | ||
| 13. | ALA3404110 | B | Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells by membrane depolarization assay | Homo sapiens | 7 | ALA3400059 | cell-based format | Scientific Literature | |
| 14. | ALA3404111 | B | Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity at 5 uM in presence of 100 nM [3H]choline by [3H]choline uptake assay | Homo sapiens | 22 | ALA3400059 | cell-based format | Scientific Literature | |
| 15. | ALA3404112 | B | Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity at 5 uM in presence of 10 uM [3H]choline by [3H]choline uptake assay | Homo sapiens | 22 | ALA3400059 | cell-based format | Scientific Literature | |
| 16. | ALA3404113 | B | Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H]choline by [3H]choline uptake assay | Homo sapiens | 22 | ALA3400059 | cell-based format | Scientific Literature | |
| 17. | ALA3404114 | B | Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]choline by [3H]choline uptake assay | Homo sapiens | 22 | ALA3400059 | cell-based format | Scientific Literature | |
| 18. | ALA3773483 | B | Inhibition of choline transporter 1 (unknown origin) | Homo sapiens | 1 | ALA3769388 | single protein format | Scientific Literature | |
| 19. | ALA3777197 | B | Binding affinity to human CHT1 transporter at 10 uM by radioligand binding assay | Homo sapiens | 1 | ALA3774360 | single protein format | Scientific Literature | |
| 20. | ALA3860686 | B | Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells at 5 uM preincubated for 15 mins followed by [3H]choline addition measured after 10 to 15 mins by scintillation proximity assay relative to control | Homo sapiens | 6 | ALA3860045 | cell-based format | Scientific Literature |
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