| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA861195 | B | Binding affinity to MCT1 by FB assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 2. | ALA869601 | B | Binding affinity to MCT1 by SPA | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 3. | ALA910516 | B | Potency at MCT1 after 0.5 hrs by SPA assay | 3 | single protein format | Scientific Literature | |||
| 4. | ALA910517 | B | Potency at MCT1 after 1 hr by SPA assay | 3 | single protein format | Scientific Literature | |||
| 5. | ALA910520 | B | Potency at MCT1 after 3 hrs by SPA assay | 3 | single protein format | Scientific Literature | |||
| 6. | ALA910521 | B | Potency at MCT1 after 24 hrs by SPA assay | 3 | single protein format | Scientific Literature | |||
| 7. | ALA910522 | B | Binding affinity to MCT1 | 13 | single protein format | Scientific Literature | |||
| 8. | ALA1226685 | B | Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione from MCT1 in human Jurkat cell membranes | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 9. | ALA1226686 | B | Displacement of [3H]5-[(3-hydroxypropyl)thio]-3-methyl-1-[2-(methyl-t)propyl-2,3-t2]-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione from human MCT1 expressed in INS1 cell membrane | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA1226689 | B | Inhibition of human MCT1 expressed in INS1 cells assessed as reduction in intracellular acidification at 10 nM after 1 hr by L-Lactate uptake based BCECF staining | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA1226692 | B | Inhibition of human MCT1-mediated L-Lactate transport in PMA-ionomycin stimulated human T cells assessed as reduction in intracellular acidification at 10 nM pretreated for 1 hr before antigen stimulation by BCECF staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3386534 | B | Binding affinity to MCT1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3363651 | B | Inhibition of MCT1 (unknown origin) overexpressed in human MCF7 cells assessed as inhibition of transporter-mediated [14C]lactate transport after 10 mins by scintillation counting | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 14. | ALA3822205 | B | Activity at MCT1 (unknown origin) using [14C]lactate by cell based lactate flux assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA3822206 | B | Inhibition of MCT1 in human Raji cells assessed as inhibition of cell proliferation after 96 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 16. | ALA4614892 | B | Inhibition of MCT1 in human A673 cells assessed as reduction in BrPA-induced cytotoxicity at 10 nM by SRB assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4886128 | B | Lactate efflux inhibition assay (SNU-398) | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 18. | ALA5234413 | B | Inhibition of MCT1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5234415 | B | Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysis | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 20. | ALA5234424 | B | Binding affinity to MCT1 (unknown origin) assessed as inhibition constant | Homo sapiens | 1 | single protein format | Scientific Literature |
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