# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA859059 | B | Binding affinity to Mcl1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA909447 | B | Displacement of FAM-Bid from human Mcl1 by FP assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA918621 | B | Displacement of FAM-Bid BH3 peptide from human Mcl1 by FP-based binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA918622 | B | Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Mcl1 by ELISA assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA888455 | B | Displacement of FAM-Bim peptide from human Mcl1 by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA2066621 | B | Binding affinity to N-terminus 8X His-tagged human Mcl1 expressed in Escherichia coli BL21 (DE3) cells after 2 hrs by fluorescence polarization assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
7. | ALA1825443 | B | Displacement of FITC labeled Bak BH3 peptide from Mcl-1 after 2 mins by Fluorescence Polarization assay | 33 | single protein format | Scientific Literature | |||
8. | ALA1827901 | B | Displacement of FAM-Bid peptide from human Mcl-1 after 30 mins by competitive fluorescence polarization assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
9. | ALA932184 | B | Inhibition of human Mcl-1 protein by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
10. | ALA1943220 | B | Binding affinity to Mcl-1 by competitive fluorescence polarization assay | 14 | single protein format | Scientific Literature | |||
11. | ALA2013885 | B | Binding affinity to Mcl-1 | 1 | single protein format | Scientific Literature | |||
12. | ALA2014668 | B | Inhibition of Mcl-1 in doxycyclin-stimulated human HeLa cells overexpressing Bad3SA assessed as increase in caspase3/7 activity at 10 uM after 6 hrs by luminescence analysis | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
13. | ALA2014669 | B | Inhibition of Mcl-1 in doxycyclin-stimulated human HeLa cells overexpressing Bad3SA assessed as increase in caspase3/7 activity at 50 uM after 6 hrs by luminescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA2014670 | B | Inhibition of Mcl-1 in human HeLa cells overexpressing Bad3SA assessed as increase in caspase3/7 activity at 10 uM after 6 hrs by luminescence analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
15. | ALA2014671 | B | Inhibition of Mcl-1 in human HeLa cells overexpressing Bad3SA assessed as increase in caspase3/7 activity at 50 uM after 6 hrs by luminescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA2014673 | B | Induction of Mcl-1-mediated apoptosis in doxycyclin-stimulated human HeLa cells expressing GFP at 10 uM after 12 hrs by Hoechst staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA2014677 | B | Induction of Mcl-1-mediated apoptosis in doxycyclin-stimulated human HeLa cells overexpressing Bad3SA at 10 uM after 12 hrs by Hoechst staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA2014678 | B | Induction of Mcl-1-mediated apoptosis in doxycyclin-stimulated human HeLa cells overexpressing Bad3SA at 1 uM after 12 hrs by Hoechst staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA2162634 | B | Inhibition of human N-terminal His8-tagged Mcl1 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BID binding after 1 to 2 hrs by fluorescence polarization assay | Homo sapiens | 15 | assay format | Scientific Literature | ||
20. | ALA2162646 | F | Antagonist activity at recombinant Mcl1 assessed as restoration of BIM BH3-induced cytochrome c release in mitochondria isolated from MDA-MB-231 cells after 1 hr by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |