| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA859059 | B | Binding affinity to Mcl1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA909447 | B | Displacement of FAM-Bid from human Mcl1 by FP assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA918621 | B | Displacement of FAM-Bid BH3 peptide from human Mcl1 by FP-based binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA918622 | B | Displacement of biotinylated Bim BH3 peptide from recombinant His-tagged Mcl1 by ELISA assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA888455 | B | Displacement of FAM-Bim peptide from human Mcl1 by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 6. | ALA932184 | B | Inhibition of human Mcl-1 protein by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 7. | ALA936497 | B | Inhibition of BH3 peptide binding to human recombinant MCL1 by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA1031852 | B | Displacement of F-BakBH3 from Mcl-1 by fluorescence polarization assay | 10 | single protein format | Scientific Literature | |||
| 9. | ALA1063018 | B | Inhibition of Bak binding to Mcl-1 by FRET assay | 10 | single protein format | Scientific Literature | |||
| 10. | ALA1055758 | B | Inhibition of recombinant His6-tagged MCL1 (171-326) expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization assay | 2 | assay format | Scientific Literature | |||
| 11. | ALA1064401 | B | Displacement of fluorescein-labeled Bak-BH3 peptide from human Mcl1 by fluorescence polarization assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA1064403 | B | Binding affinity to human Mcl1 by isothermal titration calorimetry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA1107300 | B | Inhibition of MCL1 binding to Bak by FRET assay | 3 | single protein format | Scientific Literature | |||
| 14. | ALA1121053 | B | Inhibition of Mcl1 protein by Mcl1/Bak fluorescence resonance assay | 2 | single protein format | Scientific Literature | |||
| 15. | ALA1106539 | B | Displacement of FITC-labeled Bak BH3 peptide from Mcl-1 after 30 mins by fluorescence polarization assay | 3 | single protein format | Scientific Literature | |||
| 16. | ALA1274442 | B | Binding affinity to MCL1 | 1 | single protein format | Scientific Literature | |||
| 17. | ALA1273519 | B | Displacement of F-BakBH3 from Mcl-1 after 30 mins by fluorescence polarization assay | 12 | single protein format | Scientific Literature | |||
| 18. | ALA1614321 | B | PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of myeloid cell leukemia sequence 1 (MCL1) interactions with BIM-BH3 peptide. (Class of assay: confirmatory) [Related pubchem assays: 2090 (Summary AID.), 2057 (Screening assay (MCL1 inhibitors).), 2168 (Screening assay (MCL1 inhibitors).)] | Homo sapiens | 128 | cell-based format | PubChem BioAssays | ||
| 19. | ALA1614529 | F | PUBCHEM_BIOASSAY: Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors. (Class of assay: confirmatory) [Related pubchem assays: 1022 (Primary screen preceding this dose-response assay.)] | Homo sapiens | 1,105 | assay format | PubChem BioAssays | ||
| 20. | ALA1677785 | B | Displacement of FAM-Bid from human Mcl-1 after 30 mins by fluorescence polarization assay | Homo sapiens | 14 | single protein format | Scientific Literature |
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