# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA865875 | B | Activity against CYP24 upto 20 uM | 6 | single protein format | Scientific Literature | |||
2. | ALA917755 | B | Inhibition of human CYP24 hydroxylase expressed in V79 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
3. | ALA926258 | B | Inhibition of CYP24 in human keratinocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA926260 | B | Inhibition of CYP24 | 1 | single protein format | Scientific Literature | |||
5. | ALA1055571 | B | Binding affinity to human CYP24A1 expressed in Escherichia coli assessed as catalytic efficiency after 60 mins relative 1-alpha,25-dihydroxyvitamin D3 | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA1177226 | A | Inhibition of CYP24A1 | 1 | single protein format | Scientific Literature | |||
7. | ALA1177227 | A | Inhibition of CYP24A1 in human epidermal keratinocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA1177228 | A | Inhibition of human CYP24A1 expressed in chinese hamster V79 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA1177229 | A | Inhibition of human recombinant CYP24A1 expressed in chinese hamster V79 cells using [3H-1-beta]calcitriol after 60 mins by scintillation counting | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
10. | ALA1252218 | B | Inhibition of CYP24A1 expressed in CHO cells | 14 | cell-based format | Scientific Literature | |||
11. | ALA1252220 | B | Inhibition of CYP24A1 L148F mutant expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA1252221 | B | Inhibition of CYP24A1 M416T mutant expressed in CHO cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA3383457 | B | Inhibition of N-terminally MBP-fused human CYP24A1 by cell-free assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
14. | ALA3369890 | B | Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 25 mins by HPLC method | Homo sapiens | 22 | assay format | Scientific Literature | ||
15. | ALA3369896 | B | Effect on CYP24A1 in human primary CLL cells assessed as effect on VDR-regulated GADD45alpha mRNA expression at 10 nM incubated for 24 hrs by quantitative RT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA3369897 | B | Effect on CYP24A1 in human primary CLL cells assessed as effect on VDR-regulated CDKN1A mRNA expression at 10 nM incubated for 24 hrs by quantitative RT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA3369898 | B | Effect on CYP24A1 in human primary CLL cells assessed as increase in VDR-regulated GADD45alpha mRNA expression at 100 nM incubated for 24 hrs by quantitative RT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA3369899 | B | Effect on CYP24A1 in human primary CLL cells assessed as increase in VDR-regulated CDKN1A mRNA expression at 100 nM incubated for 24 hrs by quantitative RT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA3369900 | B | Inhibition of CYP24A1 in human primary CLL cells assessed as increase in VDR-regulated GADD45alpha mRNA expression in presence of 100 nM calcitriol incubated for 24 hrs by quantitative RT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA3369901 | B | Inhibition of CYP24A1 in human primary CLL cells assessed as increase in VDR-regulated CDKN1A mRNA expression in presence of 100 nM calcitriol incubated for 24 hrs by quantitative RT-PCR method | Homo sapiens | 1 | cell-based format | Scientific Literature |