# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869399 | B | Inhibition of recombinant human AKR1C3 | Homo sapiens | 12 | ALA1141206 | single protein format | Scientific Literature | |
2. | ALA869400 | B | Inhibition of recombinant human AKR1C3 at 50 uM | Homo sapiens | 6 | ALA1141206 | single protein format | Scientific Literature | |
3. | ALA988257 | B | Inhibition of human recombinant AKR1C3 | Homo sapiens | 1 | ALA1155846 | single protein format | Scientific Literature | |
4. | ALA980735 | B | Inhibition of human recombinant type 2 3-alpha-HSD expressed in Escherichia coli JM109 | Homo sapiens | 3 | ALA1138501 | assay format | Scientific Literature | |
5. | ALA1004012 | B | Inhibition of human 17beta HSD5 mediated conversion of testosterone to delta-4-androstene-3,17-dione | Homo sapiens | 1 | ALA1156426 | single protein format | Scientific Literature | |
6. | ALA1004013 | B | Inhibition of human 17beta HSD5 in HEK cells | Homo sapiens | 3 | ALA1156426 | cell-based format | Scientific Literature | |
7. | ALA958792 | B | Inhibition of human recombinant 17beta-HSD5 expressed in intact HEK293 cells assessed as conversion of androstenedione to testosterone at 20 uM after 24 hrs | Homo sapiens | 14 | ALA1157467 | cell-based format | Scientific Literature | |
8. | ALA962456 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 0.3 uM after 18 hrs | Homo sapiens | 26 | ALA1153852 | cell-based format | Scientific Literature | |
9. | ALA962457 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone at 3 uM after 18 hrs | Homo sapiens | 26 | ALA1153852 | cell-based format | Scientific Literature | |
10. | ALA962458 | B | Inhibition of human 17beta-HSD5 expressed in HEK293 cells assessed as enzyme-mediated transformation of [14C]-4-androstene-3,17-dione in to [14C]-testosterone after 18 hrs | Homo sapiens | 12 | ALA1153852 | cell-based format | Scientific Literature | |
11. | ALA1033525 | B | Inhibition of human recombinant GST-tagged AKR1C3 expressed in Escherichia coli BL21 at 100 uM | Homo sapiens | 13 | ALA1158398 | assay format | Scientific Literature | |
12. | ALA1033527 | B | Inhibition of human recombinant GST-tagged AKR1C3 expressed in Escherichia coli BL21 | Homo sapiens | 4 | ALA1158398 | assay format | Scientific Literature | |
13. | ALA1033529 | B | Inhibition of human recombinant GST-tagged AKR1C3 expressed in Escherichia coli BL21 at 50 uM | Homo sapiens | 2 | ALA1158398 | assay format | Scientific Literature | |
14. | ALA1687512 | B | Inhibition of AKR1C3 by fluorimetric method | 12 | ALA1681639 | single protein format | Scientific Literature | ||
15. | ALA1686172 | B | Inhibition of PGF synthase in IL1-beta treated human A549 cell microsome assessed as inhibition of PGF2alpha production after 1 min in presence of 50% FBS | Homo sapiens | 5 | ALA1681669 | cell-based format | Scientific Literature | |
16. | ALA1919082 | B | Inhibition of human 17beta-HSD5 expressed in Escherichia coli assessed as radiolabeled testosterone formation using [1,2,6,7-3H]A-dione as substrate at 1 uM by scintillation counting | Homo sapiens | 1 | ALA1914369 | assay format | Scientific Literature | |
17. | ALA2025084 | B | Inhibition of recombinant AKR1C3 assessed as enzyme catalyzed oxidation of S-tetralol by fluorimetric assay | 1 | ALA2021904 | single protein format | Scientific Literature | ||
18. | ALA2025092 | B | Inhibition of AKR1C3 in human LNCaP cells assessed as reduction in testosterone formation at 10 uM using [14C]-delta4-androstene-3,17-dione substrate | Homo sapiens | 1 | ALA2021904 | cell-based format | Scientific Literature | |
19. | ALA2038586 | B | Inhibition of human recombinant AKR1C3 expressed in Escherichia coli JM109 cells using S-tetralol as substrate by fluorometry | Homo sapiens | 5 | ALA2034893 | cell-based format | Scientific Literature | |
20. | ALA2038590 | B | Inhibition of human recombinant AKR1C3 expressed in Escherichia coli JM109 cells using S-tetralol as substrate at 100 uM by fluorometry | Homo sapiens | 2 | ALA2034893 | cell-based format | Scientific Literature |