# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA861313 | Functional | Inhibition of p53-mediated increase in p21/WAF1 level at 300 nM | Mus musculus | 3 | ALA1148645 | assay format | Scientific Literature | |
2. | ALA863154 | Functional | Inhibition of p53-mediated increase in p21/WAF1 level at 30 nM | Mus musculus | 2 | ALA1148645 | assay format | Scientific Literature | |
3. | ALA1120639 | Binding | Induction of p53-dependent transcriptional activity in mouse JB6 Cl41 cells at 12.5 uM after 6 hrs | Mus musculus | 1 | ALA1158618 | cell-based format | Scientific Literature | |
4. | ALA1167274 | Binding | Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells at 125 to 500 nM by luciferase reporter gene assay | Mus musculus | 1 | ALA1165930 | cell-based format | Scientific Literature | |
5. | ALA1167275 | Binding | Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells after 24 hrs by luciferase reporter gene assay | Mus musculus | 1 | ALA1165930 | cell-based format | Scientific Literature | |
6. | ALA1167277 | Binding | Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells at 375 to 500 nM after 6 hrs by luciferase reporter gene assay relative to control | Mus musculus | 1 | ALA1165930 | cell-based format | Scientific Literature | |
7. | ALA1167278 | Binding | Inhibition of p53-mediated transcriptional activity in mouse JB6 Cl41 cells at 125 to 250 nM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 1 | ALA1165930 | cell-based format | Scientific Literature | |
8. | ALA1249429 | Binding | Inhibition of p53-induced apoptosis in gamma irradiated mouse thymocytes at 10 uM after 24 hrs by trypan blue assay | Mus musculus | 1 | ALA1240314 | cell-based format | Scientific Literature | |
9. | ALA1249842 | Binding | Inhibition of p53-mediated apoptosis in mouse fibroblast assessed as cell survival at 10 uM after 24 hrs by methylene blue assay | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
10. | ALA1249870 | Binding | Inhibition of p53-dependent transcription of puma in mouse thymocyte | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
11. | ALA1249871 | Binding | Inhibition of p53-dependent transcription of puma in gamma-stimulated mouse thymocyte | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
12. | ALA1249949 | Binding | Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic p53 concentration at 10 uM after 2 hrs | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
13. | ALA1249950 | Binding | Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as mitochondrial p53 concentration at 10 uM after 2 hrs | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
14. | ALA1249951 | Binding | Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic Bcl-2 concentration at 10 uM after 2 hrs | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
15. | ALA1249952 | Binding | Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic p21 concentration at 10 uM after 2 hrs | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
16. | ALA1249953 | Binding | Binding affinity to p53 in gamma irradiated mouse thymocyte assessed as cytosolic caspase 8 concentration at 10 uM after 2 hrs | Mus musculus | 1 | ALA1240314 | single protein format | Scientific Literature | |
17. | ALA3243361 | Binding | Inhibition of p53-dependent transcriptional activity in tumor promotion-sensitive mouse JB6 Cl41 cells after 12 hrs by luciferase-based method | Mus musculus | 11 | ALA3232964 | cell-based format | Scientific Literature | |
18. | ALA3999111 | ADME | Effect on p53 phosphorylation in mouse primary mesangial cells up to 8 uM by Western blot method | Mus musculus | 1 | ALA3997802 | assay format | Scientific Literature | |
19. | ALA3999117 | ADME | Effect on p53 phosphorylation in mouse primary mesangial cells up to 2.2 uM by Western blot method | Mus musculus | 1 | ALA3997802 | assay format | Scientific Literature |