# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3425241 | ADME | Half life in rat hepatocytes | Rattus norvegicus | 1 | ALA3421585 | cell-based format | Scientific Literature | |
2. | ALA3424982 | ADME | Intrinsic clearance in Wistar Han rat hepatocytes assessed per 10'6 cells | Rattus norvegicus | 15 | ALA3421608 | cell-based format | Scientific Literature | |
3. | ALA3429927 | ADME | Intrinsic clearance in rat hepatocytes measured per 10'6 cells | Rattus norvegicus | 22 | ALA3425438 | cell-based format | Scientific Literature | |
4. | ALA3428434 | ADME | Cytotoxicity against hepatocytes (unknown origin) | Not specified | 4 | ALA3425442 | cell-based format | Scientific Literature | |
5. | ALA3430310 | ADME | Half life in NewZealand white rabbit hepatocytes by LC-PDA-MSA analysis | Oryctolagus cuniculus | 1 | ALA3425434 | cell-based format | Scientific Literature | |
6. | ALA3430312 | ADME | Stability in NewZealand white rabbit hepatocytes assessed as compound remaining after 120 mins by LC-MS/MS analysis | Oryctolagus cuniculus | 1 | ALA3425434 | cell-based format | Scientific Literature | |
7. | ALA3539887 | ADME | Drug level in rat hepatocytes treated with carbazeran by UV chromatogram method | Rattus norvegicus | 10 | ALA3525996 | cell-based format | Scientific Literature | |
8. | ALA3538057 | ADME | Biliary excretion index in MRP2-deficient Wistar rat day 4 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature | |
9. | ALA3538058 | ADME | Biliary clearance in MRP2-deficient Wistar rat day 4 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature | |
10. | ALA3538063 | ADME | Biliary clearance in wild type Wistar rat day 4 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature | |
11. | ALA3538064 | ADME | Biliary clearance in BCRP-deficient Wistar rat day 4 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature | |
12. | ALA3538065 | ADME | Biliary clearance in Ad-siNT-infected Wistar rat day 4 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature | |
13. | ALA3538066 | ADME | Biliary clearance in BCRP-deficient Wistar rat day 6 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 2 | ALA3526085 | cell-based format | Scientific Literature | |
14. | ALA3538615 | ADME | Drug uptake in sandwich-cultured human hepatocytes lot 109 at 0.05 uM at 37 degC for 5 mins by scintillation spectroscopy in presence of 10 uM cyclosporine A OATP substrate/inhibitor (Rvb = 100 +/- 3.1 to 100 +/- 7.8%) | Homo sapiens | 1 | ALA3525928 | cell-based format | Scientific Literature | |
15. | ALA3538616 | ADME | Drug uptake in sandwich-cultured human hepatocytes lot 109 at 0.05 uM at 37 degC for 5 mins by scintillation spectroscopy in presence of 100 uM rifamycin SV OATP substrate/inhibitor (Rvb = 100 +/- 3.1 to 100 +/- 7.8%) | Homo sapiens | 1 | ALA3525928 | cell-based format | Scientific Literature | |
16. | ALA3538617 | ADME | Drug uptake in sandwich-cultured human hepatocytes lot 109 at 0.05 uM at 37 degC for 5 mins by scintillation spectroscopy in presence of 100 uM rifampicin OATP substrate/inhibitor (Rvb = 100 +/- 3.1 to 100 +/- 7.8%) | Homo sapiens | 1 | ALA3525928 | cell-based format | Scientific Literature | |
17. | ALA3538618 | ADME | Drug uptake in sandwich-cultured human hepatocytes lot 109 at 0.05 uM at 37 degC for 5 mins by scintillation spectroscopy in presence of 100 uM estrone sulfate OATP substrate/inhibitor (Rvb = 100 +/- 3.1 to 100 +/- 7.8%) | Homo sapiens | 1 | ALA3525928 | cell-based format | Scientific Literature | |
18. | ALA3539634 | ADME | Detection of compound level in rat hepatocytes treated with 25 uM of BMS-562086 after 3 hrs by HPLC analysis | Rattus norvegicus | 2 | ALA3526146 | cell-based format | Scientific Literature | |
19. | ALA3540915 | ADME | Biliary clearance in Ad-siNT-infected Wistar rat day 6 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature | |
20. | ALA3540916 | ADME | Biliary excretion index in BCRP-deficient Wistar rat day 6 sandwich-cultured hepatocytes at 5 uM after 10 mins by LC-MS/MS analysis relative to control | Rattus norvegicus | 1 | ALA3526085 | cell-based format | Scientific Literature |