# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3429142 | Functional | Anticancer activity against human LAPC4 cells assessed as inhibition of cell growth up to 10 uM after 72 hrs by trypan blue exclusion assay | Homo sapiens | 3 | ALA3425491 | cell-based format | Scientific Literature | |
2. | ALA3607513 | Functional | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as induction of cell proliferation at 0.1 uM after 3 days by MTS assay relative to control | Homo sapiens | 42 | ALA3603811 | cell-based format | Scientific Literature | |
3. | ALA3607514 | Functional | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as induction of cell proliferation at 1 uM after 3 days by MTS assay relative to control | Homo sapiens | 42 | ALA3603811 | cell-based format | Scientific Literature | |
4. | ALA861000 | Functional | Cytotoxicity against human LAPC4 cell line by MTT assay | 24 | ALA1146091 | cell-based format | Scientific Literature | ||
5. | ALA1118290 | Functional | Antitumor activity against human castration and bicalutamide-resistant LAPC4 cells xenografted in SCID mouse assessed as change in tumor volume at 10 mg/kg measured up to 20 days | Homo sapiens | 2 | ALA1155462 | organism-based format | Scientific Literature | |
6. | ALA1118291 | Functional | Antitumor activity against human castration and bicalutamide-resistant LAPC4 cells xenografted in SCID mouse assessed as change in tumor volume measured up to 50 days | Homo sapiens | 1 | ALA1155462 | cell-based format | Scientific Literature | |
7. | ALA3418513 | Functional | Antitumor activity against human LAPC4 cells xenografted in SCID mouse assessed as reduction in tumor volume at 0.15 mmol/kg, sc dosed twice daily starting 1 day after tumor cell inoculation and measured after 16 weeks of treatment | Homo sapiens | 1 | ALA3414506 | organism-based format | Scientific Literature | |
8. | ALA3418514 | Functional | Antitumor activity against human LAPC4 cells xenografted in SCID mouse assessed as tumor volume at 0.13 mmol/kg, sc dosed twice daily (Rvb = 2410.28 mm3) | Homo sapiens | 1 | ALA3414506 | organism-based format | Scientific Literature | |
9. | ALA3418515 | Functional | Antitumor activity against human LAPC4 cells xenografted in SCID mouse assessed as regression of tumor volume at 0.13 mmol/kg, sc dosed twice daily | Homo sapiens | 1 | ALA3414506 | organism-based format | Scientific Literature | |
10. | ALA3418516 | Functional | Antitumor activity against human LAPC4 cells xenografted in SCID mouse with castration assessed as regression of tumor volume at 0.13 mmol/kg, sc dosed twice daily | Homo sapiens | 1 | ALA3414506 | organism-based format | Scientific Literature | |
11. | ALA4364916 | Functional | Antiproliferative activity against AR-positive human LAPC4 cells assessed as cell viability at 40 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 8 | ALA4364252 | cell-based format | Scientific Literature | |
12. | ALA4364921 | Functional | Antiproliferative activity against AR-positive human LAPC4 cells assessed as cell viability at 10 uM measured after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 1 | ALA4364252 | cell-based format | Scientific Literature | |
13. | ALA3375049 | Functional | Cytotoxicity against human LAPC4 cells assessed as dead cells at 1 uM after 24 hrs | Homo sapiens | 11 | ALA3352437 | cell-based format | Scientific Literature | |
14. | ALA3112260 | Functional | Cytotoxicity against human LAPC4 cells after 7 days by Alamar blue staining method | Homo sapiens | 14 | ALA3108746 | cell-based format | Scientific Literature | |
15. | ALA4364939 | Functional | Antiproliferative activity against AR-positive human LAPC4 cells assessed as growth inhibition measured after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 7 | ALA4364252 | cell-based format | Scientific Literature | |
16. | ALA4407233 | ADME | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as effect on cell proliferation at 0.1 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay (Rvb = 100%) | Homo sapiens | 10 | ALA4406803 | cell-based format | Scientific Literature | |
17. | ALA4407234 | ADME | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as effect on cell proliferation at 0.5 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay (Rvb = 100%) | Homo sapiens | 10 | ALA4406803 | cell-based format | Scientific Literature | |
18. | ALA4407235 | ADME | Androgenic activity in human LAPC4 cells expressing androgen receptor assessed as effect on cell proliferation at 1 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay (Rvb = 100%) | Homo sapiens | 10 | ALA4406803 | cell-based format | Scientific Literature | |
19. | ALA4407239 | Functional | Antiproliferative activity against human LAPC4 cells expressing androgen receptor assessed as inhibition of cell proliferation at 0.1 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay relative to control | Homo sapiens | 6 | ALA4406803 | cell-based format | Scientific Literature | |
20. | ALA4407240 | Functional | Antiproliferative activity against human LAPC4 cells expressing androgen receptor assessed as inhibition of cell proliferation at 0.5 uM supplemented with fresh medium containing compounds every 3 days for 7 days by MTS assay relative to control | Homo sapiens | 6 | ALA4406803 | cell-based format | Scientific Literature |