# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA915842 | F | Activity at GPR109a in CHO cells assessed as inhibition of forskolin-induced cAMP generation | Homo sapiens | 37 | ALA1142997 | cell-based format | Scientific Literature | |
2. | ALA915846 | F | Activity at GPR109a in CHO cells assessed as inhibition of forskolin-induced cAMP generation upto 100 uM | Homo sapiens | 2 | ALA1142997 | cell-based format | Scientific Literature | |
3. | ALA890936 | B | Activity at HM74A receptor | Homo sapiens | 1 | ALA1146379 | single protein format | Scientific Literature | |
4. | ALA899634 | F | Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
5. | ALA899641 | F | Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay in relative to niacin | Homo sapiens | 27 | ALA1137460 | cell-based format | Scientific Literature | |
6. | ALA899919 | F | Agonist activity at human GPR109a receptor transfected in CHOK1 cells at 30 uM assessed as reversal of forskolin induced cAMP elevating effect by whole cell assay | Homo sapiens | 45 | ALA1137621 | cell-based format | Scientific Literature | |
7. | ALA899920 | F | Agonist activity at human GPR109a receptor transfected in CHOK1 cells assessed as reversal of forskolin induced cAMP elevating effect by whole cell assay | Homo sapiens | 2 | ALA1137621 | cell-based format | Scientific Literature | |
8. | ALA900196 | B | Displacement of [3H]niacin from human GPR109A | Homo sapiens | 18 | ALA1138322 | single protein format | Scientific Literature | |
9. | ALA900197 | B | Displacement of [3H]niacin from human GPR109A in presence of 4% human serum | Homo sapiens | 12 | ALA1138322 | single protein format | Scientific Literature | |
10. | ALA900198 | F | Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTP-gamma-S binding assay | Homo sapiens | 20 | ALA1138322 | cell-based format | Scientific Literature | |
11. | ALA924060 | F | Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test | Homo sapiens | 41 | ALA1140673 | assay format | Scientific Literature | |
12. | ALA924063 | F | Agonist activity at human cloned GPR109a receptor up to 30 uM by forskolin-stimulated cAMP production test | Homo sapiens | 25 | ALA1140673 | assay format | Scientific Literature | |
13. | ALA944044 | B | Displacement of [3H]niacin from human GPR109A | Homo sapiens | 18 | ALA1141426 | single protein format | Scientific Literature | |
14. | ALA944045 | F | Agonist activity at human GPR106A by [35S]GTPgammaS binding assay | Homo sapiens | 20 | ALA1141426 | assay format | Scientific Literature | |
15. | ALA944046 | F | Agonist activity at human GPR106A at 100 uM by [35S]GTPgammaS binding assay relative to niacin | Homo sapiens | 23 | ALA1141426 | assay format | Scientific Literature | |
16. | ALA921658 | F | Agonist activity at GPR109A receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced intracellular cAMP production by Flashplate assay | 7 | ALA1147980 | cell-based format | Scientific Literature | ||
17. | ALA921659 | F | Agonist activity at GPR109A receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced intracellular cAMP production by Flashplate assay relative to nicotinic acid | 7 | ALA1147980 | cell-based format | Scientific Literature | ||
18. | ALA921666 | B | Activation of GPR109A receptor in CHOK1 cells assessed as ERK1/2 MAP kinase activation by ELISA | 4 | ALA1147980 | cell-based format | Scientific Literature | ||
19. | ALA933836 | B | Induction of internalization of epitope-tagged GPR109A receptor expressed in COS7 cells after 30 mins | 2 | ALA1147980 | cell-based format | Scientific Literature | ||
20. | ALA933837 | B | Induction of internalization of epitope-tagged GPR109A receptor expressed in COS7 cells at 10 uM after 30 mins | 4 | ALA1147980 | cell-based format | Scientific Literature |