# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA869921 | B | Inhibition of lysophospholipase D autotaxin | Homo sapiens | 14 | single protein format | Scientific Literature | ||
2. | ALA865903 | B | Inhibition of recombinant ATX from transfected HEK293 cells | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA1806208 | B | Inhibition of human NPP2 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA1806209 | B | Inhibition of human secreted NPP2 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA2025231 | B | Inhibition of ATX-mediated human MDA-MB-231 cell migration at 10 uM after 8 hrs by Cyto Fluor spectrophotometry relative to lysophosphatidyl choline | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA2020714 | B | Inhibition of human recombinant autotaxin expressed in insect Sf9 cells using FS-3 as substrate at 1 uM preincubated for 10 mins prior substrate addition measured up to 60 mins by FRET-based analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
7. | ALA2020715 | B | Inhibition of human recombinant autotaxin expressed in insect Sf9 cells using FS-3 as substrate preincubated for 10 mins prior substrate addition measured up to 60 mins by FRET-based analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
8. | ALA887356 | B | Inhibition of human recombinant ATX at 1 uM after 16 hrs | Homo sapiens | 39 | single protein format | Scientific Literature | ||
9. | ALA887357 | B | Inhibition of human recombinant ATX at 10 uM after 16 hrs | Homo sapiens | 39 | single protein format | Scientific Literature | ||
10. | ALA887358 | B | Inhibition of human recombinant ATX at 100 uM after 16 hrs | Homo sapiens | 39 | single protein format | Scientific Literature | ||
11. | ALA1820671 | B | Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 mins measured after 5 and 25 mins by fluorometric analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
12. | ALA1820672 | B | Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate at 10 uM preincubated for 10 mins measured after 5 and 25 mins by fluorometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA1804763 | B | Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as choline release using lysophosphatidylcholine as substrate after 4 hrs by choline release assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
14. | ALA1798959 | B | Inhibition of human ATX catalytic activity in MDA-MB-231 cells using conditioned medium at 10 uM | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
15. | ALA1798960 | B | Inhibition of human ATX catalytic activity in MDA-MB-231 cells using conditioned medium | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
16. | ALA933171 | B | Inhibition of autotaxin assessed as residual enzyme activity at 1 uM relative to control | 20 | single protein format | Scientific Literature | |||
17. | ALA933172 | B | Inhibition of autotaxin assessed as residual enzyme activity at 10 uM relative to control | 20 | single protein format | Scientific Literature | |||
18. | ALA933173 | B | Inhibition of autotaxin assessed as residual enzyme activity at 100 uM relative to control | 20 | single protein format | Scientific Literature | |||
19. | ALA921041 | B | Inhibition of human autotaxin expressed in MDA-MB-435 cells assessed as fluorescent lysophosphatidyl choline analog hydrolysis at 10 uM | Homo sapiens | 146 | cell-based format | Scientific Literature | ||
20. | ALA978912 | B | Activity of human autotaxin in human MBA-MBA-435 cells assessed as effect on enzyme-mediated of FS3 hydrolysis at 0.1 uM | Homo sapiens | 35 | cell-based format | Scientific Literature |