| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA863943 | B | Inhibitory activity against MPTPB | Mycobacterium tuberculosis | 7 | single protein format | Scientific Literature | ||
| 2. | ALA854513 | B | Inhibition of Mycobacterium tuberculosis ptpb | Mycobacterium tuberculosis | 3 | single protein format | Scientific Literature | ||
| 3. | ALA1948970 | B | Competitive inhibition of Mycobacterium tuberculosis H37Rv PTP-B expressed in Escherichia coli DE3 using p-nitrophenyl phosphate as substrate preincubated for 10 mins prior substrate addition measured after 5 mins by Lineweaver-Burk plot analysis | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
| 4. | ALA1948972 | B | Inhibition of Mycobacterium tuberculosis PTP-B using p-nitrophenyl phosphate as substrate at 25 uM measured for 10 mins by spectrofluorimetry | Mycobacterium tuberculosis | 100 | single protein format | Scientific Literature | ||
| 5. | ALA1948974 | B | Inhibition of Mycobacterium tuberculosis PTP-B using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetry | Mycobacterium tuberculosis | 33 | single protein format | Scientific Literature | ||
| 6. | ALA1948979 | B | Competitive inhibition of Mycobacterium tuberculosis PTP-B using p-nitrophenyl phosphate as substrate measured for 10 mins by Lineweaver-Burk plot analysis | Mycobacterium tuberculosis | 3 | single protein format | Scientific Literature | ||
| 7. | ALA2015668 | B | Inhibition of Mycobacterium tuberculosis PTPB | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
| 8. | ALA1167757 | B | Inhibition of N-terminal histidine-tagged Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence assay | Mycobacterium tuberculosis | 1 | assay format | Scientific Literature | ||
| 9. | ALA1168591 | B | Inhibition of Mycobacterium tuberculosis PTPB at 100 uM after 20 mins by ELISA | Mycobacterium tuberculosis | 5 | single protein format | Scientific Literature | ||
| 10. | ALA1768070 | B | Inhibition of Mycobacterium tuberculosis ptpB | Mycobacterium tuberculosis | 10 | single protein format | Scientific Literature | ||
| 11. | ALA1775824 | B | Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysis | Mycobacterium tuberculosis | 3 | assay format | Scientific Literature | ||
| 12. | ALA1775826 | B | Non-competitive inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB assessed as production of p-nitrophenol from pNPP substrate by Lineweaver-Burk plot analysis | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
| 13. | ALA1775840 | B | Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by microplate spectrophotometer analysis | Mycobacterium tuberculosis | 10 | single protein format | Scientific Literature | ||
| 14. | ALA1775841 | B | Inhibition of Mycobacterium tuberculosis PTPB expressed in mouse RAW 264.7 cells assessed as restoration of IFN gamma-induced ERK1/ERK2 phosphorylation at 10 uM after 30 mins by Western blotting | Mycobacterium tuberculosis | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1775307 | B | Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB | Mycobacterium tuberculosis | 10 | single protein format | Scientific Literature | ||
| 16. | ALA1775399 | B | Competitive inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB assessed as production of p-nitrophenol from pNPP substrate by Lineweaver-Burk plot analysis | Mycobacterium tuberculosis | 2 | single protein format | Scientific Literature | ||
| 17. | ALA1775400 | B | Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB at 20 uM using pNPP as substrate | Mycobacterium tuberculosis | 18 | single protein format | Scientific Literature | ||
| 18. | ALA1775402 | B | Inhibition of Mycobacterium tuberculosis PTPB expressed in mouse RAW 264.7 cells assessed as restoration of IFN gamma-induced ERK1/ERK2 phosphorylation at 15 uM after 30 mins by Western blotting | Mycobacterium tuberculosis | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA1775403 | B | Inhibition of Mycobacterium tuberculosis PTPB expressed in mouse RAW 264.7 cells assessed as restoration of IFN gamma-induced ERK1/ERK2 phosphorylation after 30 mins by Western blotting | Mycobacterium tuberculosis | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA1775404 | B | Inhibition of Mycobacterium tuberculosis PTPB expressed in mouse RAW 264.7 cells assessed as restoration of IFN gamma-induced ERK1/ERK2 phosphorylation at 5 to 10 uM after 30 mins by Western blotting | Mycobacterium tuberculosis | 1 | cell-based format | Scientific Literature |
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