# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA859694 | B | Inhibitory activity against pig brain NAD glycohydrolase (NADase) by radiochemical Nicotinamide release assay | Sus scrofa | 4 | ALA1140425 | assay format | Scientific Literature | |
2. | ALA1285540 | B | Inhibition of human recombinant CD38 expressed in Pichia pastoris by continuous fluorometric method | Homo sapiens | 5 | ALA1275373 | assay format | Scientific Literature | |
3. | ALA1799589 | B | Inhibition of human CD38 using 20 uM 1, N6-etheno NAD+ as substrate by continuous fluorimetric method | Homo sapiens | 20 | ALA1795225 | single protein format | Scientific Literature | |
4. | ALA1799745 | B | Competitive inhibition of human CD38 active site under saturating levels of substrate NAD+ | Homo sapiens | 1 | ALA1795225 | single protein format | Scientific Literature | |
5. | ALA1799746 | B | Competitive inhibition of human CD38 active site using 20 uM NAD+ as substrate | Homo sapiens | 1 | ALA1795225 | single protein format | Scientific Literature | |
6. | ALA3371548 | B | Inhibition of human CD38 catalytic domain assessed as reduction in cADPR hydrolysis incubated for 10 mins by fluorimetric cycling assay | Homo sapiens | 6 | ALA3351721 | single protein format | Scientific Literature | |
7. | ALA3371551 | A | Drug metabolism assessed as human CD38 catalytic domain-mediated compound hydrolysis by measuring 8-NH2-N9-butyl-IDPR level at 1 mM by RP-HPLC method | Homo sapiens | 1 | ALA3351721 | single protein format | Scientific Literature | |
8. | ALA3371552 | A | Drug level assessed as human CD38 catalytic domain-mediated compound formation using 1 mM 8-NH2-N9-butyl-cIDPR by RP-HPLC method | Homo sapiens | 1 | ALA3351721 | single protein format | Scientific Literature | |
9. | ALA3371553 | A | Drug metabolism assessed as human CD38 catalytic domain-mediated compound hydrolysis at 1 mM by RP-HPLC method | Homo sapiens | 3 | ALA3351721 | single protein format | Scientific Literature | |
10. | ALA3371554 | A | Drug metabolism assessed as human CD38 catalytic domain-mediated compound hydrolysis by measuring time needed for 50% hydrolysis by RP-HPLC method | Homo sapiens | 2 | ALA3351721 | single protein format | Scientific Literature | |
11. | ALA3371555 | A | Drug metabolism assessed as human CD38 catalytic domain-mediated compound hydrolysis at 1 mM using 1 ug/mL CD38 by RP-HPLC method | Homo sapiens | 2 | ALA3351721 | single protein format | Scientific Literature | |
12. | ALA3371556 | A | Drug metabolism assessed as human CD38 catalytic domain-mediated compound hydrolysis at 1 mM using 4 mg/mL CD38 by RP-HPLC method | Homo sapiens | 2 | ALA3351721 | single protein format | Scientific Literature | |
13. | ALA3423828 | B | Inhibition of human CD38 by HPLC analysis | Homo sapiens | 29 | ALA3421574 | single protein format | Scientific Literature | |
14. | ALA3423829 | B | Inhibition of human CD38 at 100 uM by HPLC analysis relative to control | Homo sapiens | 29 | ALA3421574 | single protein format | Scientific Literature | |
15. | ALA3428359 | B | Inhibition of human CD38 extracellular domain expressed in Pichia pastoris assessed as NAD hydrolysis by colorimetric-based assay | Homo sapiens | 84 | ALA3425493 | assay format | Scientific Literature | |
16. | ALA3428361 | B | Inhibition of wild type fully glycosylated human recombinant CD38-catalyzed NAD hydrolysis | Homo sapiens | 4 | ALA3425493 | single protein format | Scientific Literature | |
17. | ALA3607749 | B | Inhibition of human CD38 extracellular domain expressed in Pichia pastoris using CHAPS and NAD by colorimetric-based assay | Homo sapiens | 71 | ALA3603832 | assay format | Scientific Literature | |
18. | ALA4222829 | B | Inhibition of recombinant human CD38 extracellular domain expressed in Pichia pastoris using NAD as substrate pretreated for 30 mins followed by substrate addition measured after 15 to 45 mins | Homo sapiens | 41 | ALA4219173 | assay format | Scientific Literature | |
19. | ALA5032487 | B | Inhibition of His-tagged human CD38 using etheno-NAD as substrate preincubated for 30 mins followed by substrate addition and further incubated for 10 mins by fluorometry analysis | Homo sapiens | 7 | ALA5030569 | single protein format | Scientific Literature | |
20. | ALA5148891 | B | Inhibition of human his tagged CD38 using N6-etheno-NAD as substrate by fluorescence microplate reader assay | Homo sapiens | 46 | ALA5143723 | single protein format | Scientific Literature |