# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA861973 | B | Inhibition of chymotrypsin-like proteasome activity of human 20S proteasome | Homo sapiens | 56 | ALA1147675 | single protein format | Scientific Literature | |
2. | ALA861979 | F | Ratio of IC50 for PC3 cells to IC50 for chymotrypsin-like proteasome activity of 20S proteasome | Homo sapiens | 23 | ALA1147675 | cell-based format | Scientific Literature | |
3. | ALA861980 | F | Ratio of IC50 for PC3 cells to Kiapp for chymotrypsin-like proteasome activity of 20S proteasome | Homo sapiens | 7 | ALA1147675 | cell-based format | Scientific Literature | |
4. | ALA869330 | B | Inhibition of chymotrypsin like activity of proteasome | 6 | ALA1147821 | single protein format | Scientific Literature | ||
5. | ALA853870 | B | Inhibition of chymotrypsin-like activity in rabbit 20S proteasome | Oryctolagus cuniculus | 1 | ALA1137366 | single protein format | Scientific Literature | |
6. | ALA853871 | B | Inhibition of chymotrypsin-like activity of proteasome in intact LnCaP cells | Homo sapiens | 1 | ALA1137366 | cell-based format | Scientific Literature | |
7. | ALA1007966 | B | Binding affinity to 20S proteasome beta5 subunit in human erythrocyte at 1 uM after 1 hr by Western blotting analysis | Homo sapiens | 1 | ALA1152217 | single protein format | Scientific Literature | |
8. | ALA1007972 | B | Binding affinity to 20S proteasome beta5 subunit in human erythrocyte at 1 uM by Western blotting analysis | Homo sapiens | 1 | ALA1152217 | single protein format | Scientific Literature | |
9. | ALA1007975 | B | Binding affinity to 20S proteasome beta5 subunit in human HeLa cell extract at 1 uM by Western blotting analysis | Homo sapiens | 1 | ALA1152217 | cell-based format | Scientific Literature | |
10. | ALA1007978 | B | Binding affinity to 20S proteasome beta5 subunit in intact human HeLa cells at 1 uM by Western blotting analysis | Homo sapiens | 1 | ALA1152217 | cell-based format | Scientific Literature | |
11. | ALA1007981 | B | Inhibition of MG132 binding to beta5 subunit of 20S proteasome in human HeLa cells at 1 uM by Western blotting analysis | Homo sapiens | 2 | ALA1152217 | cell-based format | Scientific Literature | |
12. | ALA1007983 | B | Inhibition of clasto-lactacystin binding to beta5 subunit of 20S proteasome in human HeLa cells at 1 uM by Western blotting analysis | Homo sapiens | 2 | ALA1152217 | cell-based format | Scientific Literature | |
13. | ALA1073014 | B | Displacement of fluorescent labeled MV151 from 26S proteasome beta 5 in human HEK293 cell lysate assessed as disappearance of band at 0.1 to 1 uM after 1 hr by SDS-PAGE | Homo sapiens | 3 | ALA1157550 | cell-based format | Scientific Literature | |
14. | ALA1073017 | B | Inhibition of 26S proteasome beta 5 using LLVY as substrate | 8 | ALA1157550 | single protein format | Scientific Literature | ||
15. | ALA1073022 | B | Displacement of fluorescent labeled MV151 from 26S proteasome beta 5 in human HEK293 cell lysate assessed as residual activity at 1 uM after 1 hr by SDS-PAGE | Homo sapiens | 7 | ALA1157550 | cell-based format | Scientific Literature | |
16. | ALA1070969 | B | Displacement of fluorescent labeled MV151 from 26S proteasome beta 5 in human HEK293 cell lysate assessed as residual activity at 100 uM after 1 hr by SDS-PAGE | Homo sapiens | 7 | ALA1157550 | cell-based format | Scientific Literature | |
17. | ALA1948738 | B | Binding affinity to LMPX/beta2 in human PC3 cells at 10 to 20 uM after 1.5 hrs by Western blotting | Homo sapiens | 1 | ALA1944571 | cell-based format | Scientific Literature | |
18. | ALA2188326 | B | Effect on 20S proteasome subunit beta5 chymotrypsin-like activity in human HT-29 cells at 200 nM relative to control | Homo sapiens | 1 | ALA2176951 | cell-based format | Scientific Literature | |
19. | ALA2188327 | B | Effect on 20S proteasome subunit beta5 chymotrypsin-like activity in human HT-29 cells at 100 nM relative to control | Homo sapiens | 1 | ALA2176951 | cell-based format | Scientific Literature | |
20. | ALA2188328 | B | Effect on 20S proteasome subunit beta5 chymotrypsin-like activity in human HBL2-BR cells at 100 nM relative to control | Homo sapiens | 1 | ALA2176951 | cell-based format | Scientific Literature |