| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA867716 | B | Inhibition of UGT2B17 | Homo sapiens | 27 | ALA1139014 | single protein format | Scientific Literature | |
| 2. | ALA869550 | F | Competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation | Homo sapiens | 3 | ALA1139014 | assay format | Scientific Literature | |
| 3. | ALA869551 | F | Non competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation | Homo sapiens | 3 | ALA1139014 | assay format | Scientific Literature | |
| 4. | ALA904748 | B | Inhibition of human recombinant UGT2B17 assessed as reduction of scopoletin glucuronidation | Homo sapiens | 1 | ALA1143068 | single protein format | Scientific Literature | |
| 5. | ALA904753 | B | Inhibition of human recombinant UGT2B17 at 25 uM by fluorescence spectroscopy | Homo sapiens | 1 | ALA1143068 | single protein format | Scientific Literature | |
| 6. | ALA1743337 | A | Substrate of human UDP-glucuronosyltransferase UGT2B17 | Homo sapiens | 4 | ALA1743201 | single protein format | Scientific Literature | |
| 7. | ALA1908091 | A | Specific activity of expressed human recombinant UGT2B17 | Homo sapiens | 37 | ALA1907987 | single protein format | Scientific Literature | |
| 8. | ALA3539915 | A | Drug metabolism assessed as recombinant human UGT2B17 assessed as O-glucuronidation at 100 uM incubated for 60 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA3526000 | single protein format | Scientific Literature | |
| 9. | ALA3539927 | A | Drug metabolism assessed as recombinant human UGT2B17 assessed as N-glucuronidation at 100 uM incubated for 60 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA3526000 | single protein format | Scientific Literature | |
| 10. | ALA3539951 | A | Drug metabolism assessed as recombinant human C-terminal His-tagged UGT2B17-mediated estradiol-17-glucuronide formation at 200 uM after 15 to 60 mins by HPLC analysis in presence of UDPGA | Homo sapiens | 1 | ALA3525985 | single protein format | Scientific Literature | |
| 11. | ALA3539952 | A | Drug metabolism assessed as recombinant human C-terminal His-tagged UGT2B17-mediated 13-epiestradiol-17-glucuronide formation at 200 uM after 15 to 60 mins by HPLC analysis in presence of UDPGA | Homo sapiens | 1 | ALA3525985 | single protein format | Scientific Literature | |
| 12. | ALA3539953 | A | Drug metabolism assessed as recombinant human C-terminal His-tagged UGT2B17-mediated 13-epiestradiol-3-glucuronide formation at 200 uM after 15 to 60 mins by HPLC analysis in presence of UDPGA | Homo sapiens | 1 | ALA3525985 | single protein format | Scientific Literature | |
| 13. | ALA3539960 | A | Drug metabolism assessed as recombinant human C-terminal His-tagged UGT2B17-mediated 17-epiestriol glucuronide metabolite formation after 15 to 60 mins by HPLC analysis in presence of UDPGA | Homo sapiens | 1 | ALA3525985 | single protein format | Scientific Literature | |
| 14. | ALA3537734 | A | Drug metabolism assessed as human recombinant UGT2B17-mediated (2S,3S,4S,5R,6S)-6-(2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-cyclopropylphenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid formation at 10 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA3526017 | single protein format | Scientific Literature | |
| 15. | ALA3538811 | A | Drug metabolism assessed as human UGT2B17-mediated N-glucuronide-triclocarban formation expressed in baculovirus infected insect sf9 cells incubated for 5 mins prior to UDPGA addition measured after 5 to 30 mins by LC-UV analysis | Homo sapiens | 1 | ALA3525967 | cell-based format | Scientific Literature | |
| 16. | ALA3541747 | A | Activity of human recombinant UGT2B17 expressed in insect cells assessed as enzyme mediated glucuronidation at 500 uM by LC-MS/MS method | Homo sapiens | 1 | ALA3526061 | cell-based format | Scientific Literature | |
| 17. | ALA3541762 | A | Drug metabolism assessed as human UGT2B17-mediated N'-glucuronide-triclocarban formation expressed in baculovirus infected insect sf9 cells incubated for 5 mins prior to UDPGA addition measured after 5 to 30 mins by LC-UV analysis | Homo sapiens | 1 | ALA3525967 | cell-based format | Scientific Literature | |
| 18. | ALA3534359 | A | Activity of human recombinant UGT2B17 expressed in baculovirus-infected insect cells assessed as enzyme-mediated glucuronidation per mg of protein after 10 mins in presence of UDPGA | Homo sapiens | 1 | ALA3526122 | cell-based format | Scientific Literature | |
| 19. | ALA3531819 | A | Activity of human recombinant UGT2B17 expressed in insect cells assessed as enzyme mediated glucuronidation at 12.5 uM by LC-MS/MS method | Homo sapiens | 1 | ALA3526061 | cell-based format | Scientific Literature | |
| 20. | ALA3532184 | A | Activity of human recombinant UGT2B17 expressed in insect cells assessed as enzyme mediated glucuronidation by LC-MS/MS method | Homo sapiens | 1 | ALA3526061 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!