| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1244642 | B | Binding affinity to human kallikrein 2 | Homo sapiens | 1 | ALA1240344 | single protein format | Scientific Literature | |
| 2. | ALA2172817 | B | Inhibition of human KLK2 after 1 hr by phage-display based Immunofluorometric Assay | Homo sapiens | 1 | ALA2169752 | single protein format | Scientific Literature | |
| 3. | ALA3772517 | B | Inhibition of human recombinant KLK2 expressed in Escherichia coli using Bachem I-1295 as substrate preincubated for 15 mins followed by substrate addition by microplate reader analysis | Homo sapiens | 11 | ALA3769401 | assay format | Scientific Literature | |
| 4. | ALA3772686 | B | Reversible inhibition of human recombinant KLK2 expressed in Escherichia coli using H-Pro-Phe-Arg-AMC as fluorogenic substrate at 100 times IC50 preincubated for 15 mins followed by 100 fold dilution measured for 1 hr | Homo sapiens | 3 | ALA3769401 | assay format | Scientific Literature | |
| 5. | ALA3772687 | B | Irreversible inhibition of human recombinant KLK2 expressed in Escherichia coli using H-Pro-Phe-Arg-AMC as fluorogenic substrate at 100 times IC50 preincubated for 15 mins followed by 100 fold dilution measured for 1 hr | Homo sapiens | 2 | ALA3769401 | assay format | Scientific Literature | |
| 6. | ALA3774272 | B | Inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated for 10 mins followed by substrate addition by FRET assay | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 7. | ALA3774286 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as enzyme Vmax at 2 uM by Lineweaver-Burk plot analysis (Rvb = 226 +/- 10 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 8. | ALA3774287 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as enzyme Vmax at 4 uM by Lineweaver-Burk plot analysis (Rvb = 226 +/- 10 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 9. | ALA3774288 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as enzyme Vmax at 8 uM by Lineweaver-Burk plot analysis (Rvb = 226 +/- 10 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 10. | ALA3774289 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as enzyme Vmax at 10 uM by Lineweaver-Burk plot analysis (Rvb = 226 +/- 10 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 11. | ALA3771514 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as substrate Km at 2 uM by Lineweaver-Burk plot analysis (Rvb = 0.62 +/- 0.02 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 12. | ALA3771515 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as substrate Km at 4 uM by Lineweaver-Burk plot analysis (Rvb = 0.62 +/- 0.02 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 13. | ALA3771516 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as substrate Km at 8 uM by Lineweaver-Burk plot analysis (Rvb = 0.62 +/- 0.02 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 14. | ALA3771517 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate assessed as substrate Km at 10 uM by Lineweaver-Burk plot analysis (Rvb = 0.62 +/- 0.02 uM/sec) | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 15. | ALA3771518 | B | Mixed-type inhibition of human tissue kallikrein-2 expressed in baculovirus infected insect cells using Abz-KLRSSQ-EDDnp as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA3769311 | cell-based format | Scientific Literature | |
| 16. | ALA4038139 | B | Inhibition of recombinant human C-terminal 10His-tagged KLK2 (1 to 261 residues) expressed in mouse NS0 cells using fluorogenic PFR-AMC peptide as substrate after 5 mins by fluorescence based assay | Homo sapiens | 3 | ALA4033799 | cell-based format | Scientific Literature | |
| 17. | ALA4341528 | B | Inhibition of KLK2 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4340530 | single protein format | Scientific Literature | |
| 18. | ALA4667682 | B | Inhibition of KLK2 (unknown origin) at 10 uM | Homo sapiens | 3 | ALA4665658 | single protein format | Scientific Literature |
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