# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3540833 | ADME | Apparent permeability coefficient of parent compound in hamster at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis in presence of BNPP | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
2. | ALA3540834 | ADME | Drug metabolism in hamster intestinal S9 fraction assessed as production of piperinic acid at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis in presence of BNPP | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
3. | ALA3538334 | ADME | Drug metabolism in hamster assessed as appearance rate of compound in intestine treated with 400 uM of ethyl piperate administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
4. | ALA3538335 | ADME | Absorption clearance in hamster at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
5. | ALA3538336 | ADME | Degradation clearance in hamster at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
6. | ALA3538337 | ADME | Apparent permeability coefficient of compound in hamster treated with 400 uM of ethyl piperate administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
7. | ALA3538338 | ADME | Apparent permeability coefficient of parent compound in hamster at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
8. | ALA3538608 | ADME | Drug metabolism in hamster assessed as production of piperinic acid at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
9. | ALA3538609 | ADME | Drug metabolism in hamster assessed as appearance rate of compound in portal vein treated with 400 uM of ethyl piperate administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis in presence of BNPP | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
10. | ALA3538610 | ADME | Drug metabolism in hamster assessed as appearance rate of parent compound in portal vein at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis in presence of BNPP | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
11. | ALA3538611 | ADME | Drug metabolism in hamster assessed as disappearance rate of parent compound in intestine at 400 uM administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis in presence of BNPP | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
12. | ALA3541230 | ADME | Drug metabolism in hamster assessed as appearance rate of compound in intestine treated with 400 uM of ethyl piperate administered as intestinal single-pass perfusion up to 1 hr by LC-MS/MS analysis in presence of BNPP | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
13. | ALA3539047 | ADME | MRT (0 to t) in hamster at 30 mg/kg, po | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
14. | ALA3539048 | ADME | Tmax in hamster at 30 mg/kg, po | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
15. | ALA3539049 | ADME | Oral bioavailability in hamster at 30 mg/kg | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
16. | ALA3539050 | ADME | AUC (0 to t) in hamster at 10 mg/kg, iv | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
17. | ALA3539051 | ADME | AUC (0 to t) in hamster at 30 mg/kg, po | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
18. | ALA3539052 | ADME | Cmax in hamster at 30 mg/kg, po | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
19. | ALA3539053 | ADME | MRT (0 to t) in hamster at 10 mg/kg, iv | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature | |
20. | ALA3539054 | ADME | Elimination half life in hamster at 10 mg/kg, iv | Cricetinae | 1 | ALA3526108 | organism-based format | Scientific Literature |