# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3607872 | Functional | Cytotoxicity against human MeWo cells after 48 hrs by CellTiter-Blue assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
2. | ALA3607878 | Functional | Inhibition of cell migration in human MeWo cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
3. | ALA3607882 | Functional | Inhibition of cell migration in human MeWo cells assessed as gap closure distance at 5 uM after 24 hrs by wound healing assay in presence of 1 uM of LPA | Homo sapiens | 1 | ALA3603761 | cell-based format | Scientific Literature | |
4. | ALA3607883 | Functional | Cytotoxicity against human MeWo cells assessed as reduction of cell viability after 48 hrs by CellTiter-Blue assay | Homo sapiens | 2 | ALA3603761 | cell-based format | Scientific Literature | |
5. | ALA3608190 | Functional | Antitumor activity against human MeWo cells xenografted in athymic nude mouse assessed as reduction of KC/CXCL-1 level in serum at 50 mg/kg, ip administered every other day of 21 days post tumor cell injection | Homo sapiens | 1 | ALA3603761 | organism-based format | Scientific Literature | |
6. | ALA3608191 | Functional | Antitumor activity against human MeWo cells xenografted in athymic nude mouse assessed as necrosis in tumor at 50 mg/kg, ip administered every other day of 21 days post tumor cell injection up to 48 days followed by administered 40 mg/kg, ip using hematoxylin and eosin staining | Homo sapiens | 1 | ALA3603761 | organism-based format | Scientific Literature | |
7. | ALA3608192 | Functional | Antitumor activity against human MeWo cells xenografted in athymic nude mouse assessed as necrotic endothelial cells at 50 mg/kg, ip administered every other day of 21 days post tumor cell injection up to 48 days followed by administered 40 mg/kg, ip using hematoxylin and eosin staining | Homo sapiens | 1 | ALA3603761 | organism-based format | Scientific Literature | |
8. | ALA3608193 | Functional | Antitumor activity against human MeWo cells xenografted in athymic nude mouse assessed as reduction of ATX level in serum at 50 mg/kg, ip administered every other day of 21 days post tumor cell injection | Homo sapiens | 1 | ALA3603761 | organism-based format | Scientific Literature | |
9. | ALA3608194 | Functional | Antitumor activity against human MeWo cells xenografted in athymic nude mouse at 30 mg/kg, ip administered every other day of 21 days post tumor cell injection | Homo sapiens | 2 | ALA3603761 | organism-based format | Scientific Literature | |
10. | ALA3608195 | Functional | Antitumor activity against human MeWo cells xenografted in athymic nude mouse assessed as reduction of ATX level in serum at 30 mg/kg, ip administered every other day of 21 days post tumor cell injection | Homo sapiens | 2 | ALA3603761 | organism-based format | Scientific Literature | |
11. | ALA860090 | Functional | Antiproliferative activity against human MeWo cells | Homo sapiens | 6 | ALA1147810 | cell-based format | Scientific Literature | |
12. | ALA1777357 | Functional | Cytotoxicity against human MeWo cells assessed as cell growth inhibition at 5 to 10 uM after 72 hrs by MTT assay | Homo sapiens | 2 | ALA1773023 | cell-based format | Scientific Literature | |
13. | ALA1777425 | Functional | Antiproliferative activity against human MeWo cells expressing wild type b-Raf | Homo sapiens | 1 | ALA1772974 | cell-based format | Scientific Literature | |
14. | ALA1794513 | Functional | PUBCHEM_BIOASSAY: Counterscreen of A1 inhibitors in unprimed human MEWO cells Measured in Cell-Based System Using Plate Reader - 2045-06_Inhibitor_Dose_DryPowder_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2526] | Homo sapiens | ⋯ | ALA1201862 | cell-based format | PubChem BioAssays | |
15. | ALA1794558 | Functional | PUBCHEM_BIOASSAY: Secondary assay of A1 inhibitors in Trichostatin A primed human MEWO cells Measured in Cell-Based System Using Plate Reader - 2045-07_Inhibitor_Dose_DryPowder_Activity_Set2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2526] | Homo sapiens | 4 | ALA1201862 | cell-based format | PubChem BioAssays | |
16. | ALA3384254 | Functional | Cytotoxicity against human MeWo cells at 1.6 to 100 ug/ml after 72 hrs by crystal violet assay | Homo sapiens | 34 | ALA3351493 | cell-based format | Scientific Literature | |
17. | ALA979708 | Functional | Cytotoxicity against human MEWO cells assessed as fraction of viable cells after 72 hrs relative to control | Homo sapiens | 11 | ALA1149823 | cell-based format | Scientific Literature | |
18. | ALA2338928 | ADME | Cytotoxicity against human MeWo cells after 72 hrs by crystal violet staining method | Homo sapiens | 7 | ALA2331445 | cell-based format | Scientific Literature | |
19. | ALA2363448 | Functional | SANGER: Inhibition of human Mewo cell growth in a cell viability assay. | Homo sapiens | 98 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | |
20. | ALA2416154 | Functional | Antitubulinic activity in human MeWo cells assessed as blockade in G2/M phase at 3 X IC50 after 16 hrs by propidium iodide staining-based FACS analysis | Homo sapiens | 5 | ALA2413031 | cell-based format | Scientific Literature |