| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA871558 | F | Decrease in viability of NSC cells at 18.76 uM for 24 hrs in presence of bFGF | Rattus norvegicus | 1 | ALA1146877 | cell-based format | Scientific Literature | |
| 2. | ALA871559 | F | Decrease in viability of NSC cells at 37.53 uM for 48 hrs in presence of bFGF | Rattus norvegicus | 1 | ALA1146877 | cell-based format | Scientific Literature | |
| 3. | ALA871560 | F | Decrease in viability of NSC cells at 56.29 uM for 72 hrs in presence of bFGF | Rattus norvegicus | 1 | ALA1146877 | cell-based format | Scientific Literature | |
| 4. | ALA871561 | F | Induction of apoptosis in NSC cells by TUNEL assay | Rattus norvegicus | 1 | ALA1146877 | cell-based format | Scientific Literature | |
| 5. | ALA871562 | F | Induction of necrosis in NSC cells assessed as lactate dehydrogenase release at 56.29 uM within 72 hrs relative to control | Rattus norvegicus | 1 | ALA1146877 | cell-based format | Scientific Literature | |
| 6. | ALA871563 | F | Inhibition of reactive oxygen species accumulation in NSC cells relative to control | Rattus norvegicus | 1 | ALA1146877 | cell-based format | Scientific Literature | |
| 7. | ALA1809858 | F | Induction of NSC proliferation assessed as ATP level | 2 | ALA1806482 | cell-based format | Scientific Literature | ||
| 8. | ALA1925671 | F | Induction of Sprague-Dawley rat embryonic cortex NSC differentiation assessed as GFAP-positive cells at 5 uM after 4 days by immunocytochemistry analysis relative to control | Rattus norvegicus | 6 | ALA1921751 | cell-based format | Scientific Literature | |
| 9. | ALA1925672 | F | Induction of Sprague-Dawley rat embryonic cortex NSC differentiation assessed as TuJ1-positive cells at 5 uM after 4 days by immunocytochemistry analysis | Rattus norvegicus | 6 | ALA1921751 | cell-based format | Scientific Literature | |
| 10. | ALA1925673 | A | Cytotoxicity against Sprague-Dawley rat embryonic cortex NSC assessed as changes in morphology at 5 uM after 4 days by microscopic analysis | Rattus norvegicus | 1 | ALA1921751 | cell-based format | Scientific Literature | |
| 11. | ALA1925674 | A | Cytotoxicity against Sprague-Dawley rat embryonic cortex NSC assessed as reduction in nuclei count at 5 uM after 4 days using DAPI staining by fluorescent microscopic analysis | Rattus norvegicus | 1 | ALA1921751 | cell-based format | Scientific Literature | |
| 12. | ALA1925675 | F | Induction of GFAP mRNA expression in Sprague-Dawley rat embryonic cortex NSC at 5 uM after 1 day by RT-PCR analysis relative to control | Rattus norvegicus | 6 | ALA1921751 | cell-based format | Scientific Literature | |
| 13. | ALA1925676 | F | Induction of S100 mRNA expression in Sprague-Dawley rat embryonic cortex NSC at 5 uM after 1 day by RT-PCR analysis relative to control | Rattus norvegicus | 6 | ALA1921751 | cell-based format | Scientific Literature | |
| 14. | ALA1925677 | F | Induction of beta3 tubulin mRNA expression in Sprague-Dawley rat embryonic cortex NSC at 5 uM after 1 day by RT-PCR analysis | Rattus norvegicus | 6 | ALA1921751 | cell-based format | Scientific Literature | |
| 15. | ALA2025123 | F | Neurogenic activity in rat hippocampal NSC assessed as increase in beta-tubulin after 24 hrs by DAPI staining-based immunocytometric analysis | Rattus norvegicus | 5 | ALA2021862 | cell-based format | Scientific Literature | |
| 16. | ALA2444912 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of bax mRNA at 5 to 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | ALA2439975 | cell-based format | Scientific Literature | |
| 17. | ALA2444913 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of bcl2 mRNA at 5 to 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | ALA2439975 | cell-based format | Scientific Literature | |
| 18. | ALA2444914 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of bax mRNA at 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | ALA2439975 | cell-based format | Scientific Literature | |
| 19. | ALA2444915 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of bcl2 mRNA at 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | ALA2439975 | cell-based format | Scientific Literature | |
| 20. | ALA2444916 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of mRNA ratio of bcl2 to bax at 5 to 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | ALA2439975 | cell-based format | Scientific Literature |
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