| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA867944 | F | Inhibition of human coronavirus 229E 3CL protease | Human coronavirus 229E | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA2445767 | F | Antiviral activity against Coronavirus 229E infected in human HG23 cells | Human coronavirus 229E | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA5255429 | F | Antiviral activity against HCoV-229E harboring luciferase reporter gene infected in human Huh-7 cells assessed as reduction in viral replication pre-incubated for 1 hrs followed by replacement with fresh media for 6 hrs by renilla luciferase based luminometer analysis | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA5255430 | F | Antiviral activity against HCoV-229E harboring luciferase reporter gene infected in human Huh-7 cells expressing TMPRSS2 assessed as reduction in viral replication pre-incubated for 1 hrs followed by replacement with fresh media for 6 hrs by renilla luciferase based luminometer analysis | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA5255432 | F | Antiviral activity against HCoV-229E harboring luciferase reporter gene infected in human Huh-7 cells assessed as reduction in viral replication upto 50 uM pre-incubated for 1 hrs followed by replacement with fresh media for 6 hrs by renilla luciferase based luminometer analysis | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA5255433 | F | Antiviral activity against HCoV-229E harboring luciferase reporter gene infected in human Huh-7 cells expressing TMPRSS2 assessed as reduction in viral replication upto 50 uM pre-incubated for 1 hrs followed by replacement with fresh media for 6 hrs by renilla luciferase based luminometer analysis | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3994808 | F | Antiviral activity against Human coronavirus 229E infected in HEL cells assessed as reduction in virus-induced cytopathogenicity | Human coronavirus 229E | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4124853 | F | Antiviral activity against Human coronavirus 229E infected in HEL cells assessed as inhibition of virus-induced cytopathicity | Human coronavirus 229E | 17 | organism-based format | Scientific Literature | ||
| 9. | ALA4155839 | F | Antiviral activity against Human coronavirus 229E infected in human HEL299 cells assessed as inhibition of virus-induced cytopathic effect after 3 to 6 days by MTS assay | Human coronavirus 229E | 23 | organism-based format | Scientific Literature | ||
| 10. | ALA4196865 | F | Antiviral activity against Human coronavirus 229E infected in HEL cells assessed as reduction in viral cytopathic effect | Human coronavirus 229E | 10 | organism-based format | Scientific Literature | ||
| 11. | ALA4269058 | F | Antiviral activity against Human coronavirus 229E infected in HEL cells assessed as reduction in virus-induced pathogenicity after 3 days by microscopic method | Human coronavirus 229E | 30 | organism-based format | Scientific Literature | ||
| 12. | ALA4275443 | F | Antiviral activity against Human coronavirus 229E infected in HEL299 cells assessed as reduction in virus induced cytopathic effect after 5 days by microscopic method | Human coronavirus 229E | 18 | organism-based format | Scientific Literature | ||
| 13. | ALA4275445 | F | Antiviral activity against Human coronavirus 229E infected in human A549 cells assessed as reduction in virus RNA level after 3 days by qRT-PCR method | Human coronavirus 229E | 18 | organism-based format | Scientific Literature | ||
| 14. | ALA4376319 | F | Antiviral activity against Human coronavirus 229E | Human coronavirus 229E | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA4404500 | F | Antiviral activity against Human coronavirus 229E infected in HuH7 cells expressing T7 RNA polymerase assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by Alamar blue based assay | Human coronavirus 229E | 6 | organism-based format | Scientific Literature | ||
| 16. | ALA4409493 | F | Antiviral activity against Human coronavirus 229E infected in human HELF cells assessed as reduction in virus-induced cytopathogenicity incubated for 7 days by microscopic analysis | Human coronavirus 229E | 15 | organism-based format | Scientific Literature | ||
| 17. | ALA4703764 | F | Antiviral activity against Human coronavirus 229E infected in human MRC5 cells assessed as reduction in virus-induced cytopathogenicity incubated for 4 days by XTT dye based assay | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4703772 | F | Antiviral activity against Human coronavirus 229E infected in human MRC5 cells assessed as reduction in virus-induced cytopathogenicity incubated for 4 days in presence of p-glycoprotein inhibitor CP100356 by XTT dye based assay | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4712028 | F | Antiviral activity against HCoV-229E infected in human MRC5 cells incubated for 2 hrs by XTT method | Human coronavirus 229E | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4723129 | F | Antiviral activity against HCoV-229E harboring GFP infected in human Huh-7 cells treated 1 hr prior to viral infection by fluorometric analysis | Human coronavirus 229E | 2 | organism-based format | Scientific Literature |
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